2-butyl-4-chloro-5-formylimidazole CAS 83857-96-9

Product Name: 2-Butyl-4-chloro-5-formylimidazole

CAS: 83857-96-9

Formula: C8H11ClN2O

Molecular Weight: 186.64

2-Butyl-4-chloro-5-formylimidazole  Structure:2-Butyl-4-chloro-5-formylimidazole Structure

Appearance: Little-yellow crystalline powder

Purity: 98.0%~101.0%

Application scenarios

1. Pharmaceutical Synthesis Intermediates (Main Applications)
This is the most core and clearly defined industrial use of this compound.

Antihypertensive Drug Synthesis: It is a key intermediate in the synthesis of angiotensin II receptor antagonists (sartan drugs).

Losartan: It is a key synthetic intermediate for losartan.

Satan Drugs: It is generally widely classified as a common intermediate for sartan drugs.

Other Drug Related Applications: According to patent information, it can be used as an intermediate or starting material for the synthesis of other bioactive compounds (such as glucagon receptor modulators).

2. Biomedical Research Applications
These applications are currently mostly in the laboratory research stage.

Antibacterial and Anticancer Activity Studies:

Metal complexes of its derivatives (such as thiourea and Schiff bases) have shown antibacterial activity against some Gram-positive and Gram-negative bacteria in studies.

Metal complexes of some derivatives (such as Cu(II) and Ni(II) complexes) have shown anticancer activity against the breast cancer cell line (MDA-MB 231) in in vitro studies.

Enzyme Inhibitor Research: Studies have used its derivatives to design and synthesize novel peptides and evaluate their potential as angiotensin-converting enzyme inhibitors.

3. Materials Science Applications
Corrosion Inhibitors: Its derivatives (such as Schiff bases) have been explored as metal corrosion inhibitors in laboratory studies. For example, studies have shown that they inhibit the corrosion of low-carbon steel in acidic media.

4. Chemical Synthesis and Industrial Applications
General Organic Synthesis Building Blocks: Due to their unique chemical structure (containing both chlorine and aldehyde groups), they can serve as important organic synthesis intermediates for constructing more complex heterocyclic compounds or functional molecules.

Agrochemical Development: Patent information shows that molecules containing this compound’s structural units are being developed as potential fungicides and plant growth regulators.

Description

2-butyl-4-chloro-5-formylimidazole CAS 83857-96-9

Test Items Specification
Appearance Little – yellow crystalline powder
Purity 98.0%~101.0%
Content of PAA 1%max
Content of BCM 1%max
Maximum single unknown impurity 0.5%max
Total impurity 1%max
Bulk Density g/cm 1.03~1.10

2-Butyl-4-chloro-5-formylimidazole Usage

2-Butyl-4-chloro-5-formylimidazole can be used as an antihypertensive drug for losartan.

 

2-Butyl-4-chloro-5-formylimidazole Package

25kg/fiber drum.

 

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