环戊酮 CAS 120-92-3

化学名称环戊酮

化学文摘社编号:120-92-3

分子式: C5H8OC5H8O

分子量: 84.12

外观透明液体

化验:99.5%

分子结构:image.png

Cyclopentanone Application scenarios

1. As a core intermediate in organic synthesis, it is used to prepare various fine chemicals (its primary use).

Synthetic pharmaceutical intermediates: These are key precursors for many antibacterial, antiviral, and anti-anxiety drugs, such as the synthesis of the antiepileptic drug gabapentin and the antidepressant moclobemide, as well as side-chain intermediates for antibacterial drugs. They can also be used to prepare intermediates for antihistamines and lipid-lowering drugs, primarily utilizing the addition and reduction properties of their ketone carbonyl groups in the reactions.

Synthetic pesticide intermediates: Used to produce highly effective and low-toxicity pesticides, including insecticides (such as pyrethroid derivatives), fungicides (such as heterocyclic fungicides for controlling fungal diseases in crops), and herbicides. They can enhance the activity and targeting of pesticides while reducing environmental toxicity.

Monomers for Synthetic Polymers: Used to prepare specialty resins (such as polycyclopentanone resin), polyesters, polyurethanes, etc. These polymers possess characteristics such as high and low temperature resistance, corrosion resistance, and high strength, making them suitable for manufacturing components in aerospace and high-end machinery. They can also be used to synthesize cyclopentene derivatives as rubber modifiers, improving the wear resistance and elasticity of rubber.

2. Applications in the Fragrance and Flavor Industry

Direct Use in Fragrance Blending: Cyclopentanone itself has a slight minty aroma and the characteristic soft scent of ketones. It can be used in small quantities to blend minty, fruity, and woody fragrances in daily-use fragrances (such as perfumes, soaps, and laundry detergents), playing a supporting role in enhancing and fixing the fragrance.

Synthetic Intermediates for High-Grade Fragrances: It is a key raw material for preparing sandalwood fragrances (such as sandalwood ethers and sandalwood esters). Sandalwood fragrances have a long-lasting and elegant aroma, widely used in the core blending of high-end perfumes and cosmetic fragrances. Simultaneously, it can be used to synthesize other alicyclic fragrances, compensating for the insufficient production of natural fragrances.

3. Solvent Uses

As a specialty solvent, it dissolves resins, oils, rubber, and other substances. Being an alicyclic ketone solvent, its solubility is superior to some aliphatic solvents, and its volatility is moderate. It is commonly used in the formulation of high-end coatings and inks, improving the leveling and adhesion of coatings, and is suitable for coating precision instruments and high-end furniture.

It is a commonly used solvent in laboratory organic synthesis, especially suitable for reactions requiring weakly polar ketone solvents. It does not undergo side reactions with most reactants, facilitating subsequent product separation and purification.

4. Other Industrial and Scientific Applications

Preparation of Fine Chemical Additives: For example, it can be used to synthesize lubricating oil additives, improving the oxidation resistance and anti-wear properties of lubricating oils and extending the service life of mechanical equipment; it can also be used to synthesize electroplating brighteners for metal electroplating processes, resulting in more uniform and glossy coatings.

Basic Raw Material in Scientific Research: Used to study the chemical reaction mechanisms of cyclopentane derivatives and develop novel functional compounds. It is also used as a standard for qualitative and quantitative analysis in chemical and pharmaceutical testing fields.

A small amount is used to prepare dye intermediates and synthesize alicyclic dyes. These dyes have bright colors and good lightfastness, and are suitable for dyeing synthetic fibers.

描述

环戊酮 CAS 120-92-3

密度: 0.951 克/厘米

熔点:- 51 C

沸点: 130-131 摄氏度

折射率1.436-1.438

闪点:31 C

水溶性:不溶于水。

 

环戊酮的 COA

项目

标准

外观

透明液体

颜色(Hazen 编号)

≦10

纯度 (GC )

≧99.5%

酸值(mgKOH/g)

≦0.5%

杂质总量

≦0.5%

含水量

≦0.5%

环戊酮的用途

1.以环戊酮和正戊醛为原料,先经过醛醇缩合,然后脱水生成戊基环戊酮,再经过选择性催化加氢生成戊基环戊酮,具有浓郁的花果香味,并带有茉莉花香味。它可用于日用化学香料配方。用量可小于 20%。IFRA 没有限制。

2.以正己醛和环戊酮为原料,先进行缩合,然后选择性氢化,得到己基环戊酮。己基环戊酮具有浓郁的茉莉花香和果香,可用于香水香料中。而在其他各种日化香精配方中,用量也在 5% 以内。IFRA 没有限制。

3.以石蜡热解或相应醇脱水得到的 1-戊烯或 1-庚烯为原料,在过氧化二叔丁酯作为引发剂的情况下,与环戊酮发生自由基加成反应,生成 2-戊基环戊酮(或 2-庚基环戊酮),经氧化扩环后成为δ-癸内酯(或δ-月桂内酯)。

4.以环戊酮为起始原料的合成路线最具工业生产价值。环戊酮首先与正戊醛发生醛醇缩合,缩合产物经脱水和选择性氢化成为 2-戊基环戊酮,最后经氧化扩环成为δ-癸内酯。

5.δ-癸内酯主要用于食用香精配方。它被认为具有天然奶油的特征风味。在此之前,调香师长期以来只能使用双乙酰和香兰素等单体香料作为配制奶油香精的主要原料。然而,人们普遍认为配制出来的奶油香精在口感或风味上远远不如天然产品。只有使用δ-癸内酯,奶油香味才能鲜明,特别是将δ-癸内酯和δ-月桂内酯一起作为主要香料原料时,配制出的奶油香精的风味和效果会更好。

6.以环戊酮和戊醛为原料,缩合生成 2-(1-羟基)戊基环戊酮,与丙二酸二甲酯反应,在 160~180℃ 下水解、脱羧、酯化,即可得到二氢茉莉酮酸甲酯。二氢茉莉酸甲酯是我国 GB2760-1996 暂准使用的食品香料。其香味优于天然茉莉酸甲酯,性质相对稳定。

环戊酮的包装和运输

包装:200 公斤/桶

交货期:3-5 个工作日内交货

 

环戊酮储存

避免光照和干燥。

 

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