hydroxypropyl methylcellulose phthalate cas 9050-31-1

hydroxypropyl methylcellulose phthalateQuick Details

Product Name: hydroxypropyl methylcellulose phthalate

CAS No: 9050-31-1

Molecular Formula: C14H16N4

Molecular Weight: 240.30364

Appearance: Colorless or light yellow liquid

Category:

Application scenarios

1. Enteric Coating Agent:
This is the most important application of HPMCP. It remains stable and insoluble in the acidic environment of the stomach, thus protecting the drug or preventing gastric irritation. When the preparation enters the small intestine (where the pH is typically ≥5.0-5.5), it dissolves rapidly and releases the drug.

2. Controlled-Release Material for Sustained-Release Preparations:
Due to its pH-dependent solubility, HPMCP can be used to design sustained-release systems that release drugs in different parts of the intestine, extending the duration of drug action.

3. Masking Unpleasant Drug Taste:
By utilizing its insolubility in the mouth (neutral pH), coating tablets or granules with HPMCP can effectively mask the bitter or unpleasant taste of the drug.

4. Binder in Pharmaceutical Preparations:
It can be used as a binder in the preparation of tablets or granules.

5. Film-Forming Material for Microcapsules:
It is used to encapsulate active ingredients in the preparation of microcapsule formulations.

Description

hydroxypropyl methylcellulose phthalateTypicalProperties

Test Items Specification
Appearance Colorless or light yellow liquid
Viscosity, mPa·S(25℃) 30-70
Anhydride Group Content,% ≥41.0
Freezing Point,℃ ≤-15
Volatile Content,% ≤1.0
Free Acid,% ≤1.0

hydroxypropyl methylcellulose phthalateUsage

Pharmaceutical excipients; organic raw materials; raw materials;

  1. Pharmaceutical Industry: Hydroxypropyl Methylcellulose Phthalate, with CAS number 9050-31-1, is commonly used in the pharmaceutical industry. It serves as an enteric coating material for oral dosage forms, protecting drugs from gastric acid and releasing them in the intestines.
  2. Enteric Coating Applications: This compound finds applications in enteric coating formulations. HPMCP is utilized to modify the release profile of drugs, preventing them from being released in the stomach and ensuring targeted release in the intestines.
  3. Pharmaceutical Formulations: Hydroxypropyl Methylcellulose Phthalate is used in various pharmaceutical formulations. It contributes to the development of dosage forms with improved stability, solubility, and controlled release properties.
  4. Drug Delivery Systems: In drug delivery systems, HPMCP is employed to enhance the bioavailability and effectiveness of certain drugs. It is often used in formulations where a delayed or targeted release is desired.

hydroxypropyl methylcellulose phthalatePackage

According to customer requirements.

hydroxypropyl methylcellulose phthalateStorage

Sheltered, dry, dark place for storage.

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