(3r,4s)-1-benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone CAS 149249-91-2

Chemical Name: (3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone

CAS No.: 149249-91-2

Molecular Formula: C22H27NO3Si

Molecular Weight: 381.54

MolecularStructure:PACLITAXEL SIDE CHAIN NO 2 Structure

Appearance: Colorless or pale yellow oil; white powder

Application scenarios

1. Pharmaceutical Intermediates

These intermediates serve as key building blocks for the synthesis of more complex chiral drugs, particularly those containing a β-lactam core structure (such as certain antibiotics and protease inhibitors). Search results highlight the use of similar azacyclobutanone intermediates for the synthesis of chiral drug precursors.

2. Chiral Synthetons

Their (3R,4S) absolute configuration allows for asymmetric synthesis as starting materials or intermediates for introducing specific chiral centers.

3. Chemical Synthesis Research

In organic chemistry methodology research, they may serve as model substrates for developing novel synthetic methods (such as new cyclization, functional group transformation, or protecting group strategies).

Description

(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone

Items

Result

Appearance

Colorless or pale yellow oil; white powder

Identification(HPLC)

The retention time of the majoy

Water

Not more than 1.0%

Purity

Not less than 95.0%

 

(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone Usage

It is the best natural anti-cancer drug that has been discovered and has been widely used in the treatment of breast cancer, ovarian cancer and some head and neck cancers and lung cancer.

 

(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinone Packaging and Shipping

Packing(oil): 10g/bottle 100g/bottle 500g/bottle 1kg/bottle

Packing(powder):500g/Bag 100g/bag 50g/bag

 

(3R,4S)-1-Benzoyl-4-phenyl-3-[(triethylsilyl)oxy]-2-azetidinoneStorage

Oil: Stored in a cool dry and ventilated place away from sunlight and heat

Powder: Keep in-15℃.

 

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