{"id":6829,"date":"2024-04-10T01:59:41","date_gmt":"2024-04-10T01:59:41","guid":{"rendered":"https:\/\/longchangchemical.com\/?post_type=product&p=6829"},"modified":"2025-12-17T02:18:24","modified_gmt":"2025-12-17T02:18:24","slug":"beta-nicotinamide-mononucleotide-cas-1094-61-7","status":"publish","type":"product","link":"https:\/\/longchangchemical.com\/zh\/product\/beta-nicotinamide-mononucleotide-cas-1094-61-7\/","title":{"rendered":"\u70df\u9170\u80fa\u5355\u6838\u82f7\u9178 CAS 1094-61-7"},"content":{"rendered":"

\u03b2-\u70df\u9170\u80fa\u5355\u6838\u82f7\u9178\u901f\u67e5\u8be6\u60c5<\/strong><\/p>\n

\u5316\u5b66\u540d\u79f0\u03b2-\u70df\u9170\u80fa\u5355\u6838\u82f7\u9178<\/p>\n

\u5316\u5b66\u6587\u6458\u793e\u7f16\u53f7\uff1a1094-61-7<\/p>\n

\u5206\u5b50\u5f0f\uff1a C11H15N2O8PC11H15N2O8P<\/p>\n

Beta-Nicotinamide MononucleotideStructure\uff1a\"\u03b2-\u70df\u9170\u80fa\u5355\u6838\u82f7\u9178\u7ed3\u6784\"<\/p>\n

\u5206\u5b50\u91cf\uff1a 334.22<\/p>\n

\u5916\u89c2\u767d\u8272\u7c89\u672b<\/p>\n

Assay:97%~100.0%<\/p>\n

\u03b2-\u70df\u9170\u80fa\u5355\u6838\u82f7\u9178\u7684\u5178\u578b\u7279\u6027<\/strong><\/p>\n\n\n\n\n\n\n\n\n\n
\u9879\u76ee<\/td>\n\u89c4\u683c<\/td>\n<\/tr>\n
\u5916\u89c2<\/td>\n\u767d\u8272\u7c89\u672b<\/td>\n<\/tr>\n
\u6eb6\u6db2\u5916\u89c2\uff085% w\/v \u6c34\u6eb6\u6db2\uff09<\/td>\n\u65e0\u8272\u81f3\u6de1\u9ec4\u8272\u900f\u660e<\/td>\n<\/tr>\n
\u6c34<\/td>\n\u22646%<\/td>\n<\/tr>\n
\u7837<\/td>\n\u22641 ppm<\/td>\n<\/tr>\n
\u91cd\u91d1\u5c5e<\/td>\n\u226410 ppm<\/td>\n<\/tr>\n
\u5316\u9a8c<\/td>\n97%~100.0%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u03b2-\u70df\u9170\u80fa\u5355\u6838\u82f7\u9178\u7528\u9014<\/strong><\/p>\n

\u6297\u8870\u8001\u7814\u7a76\uff0c\u6297\u8870\u8001\u4fdd\u5065\u4ea7\u54c1\u539f\u6750\u6599<\/p>\n

\u03b2-\u70df\u9170\u80fa\u5355\u6838\u82f7\u9178\u5305\u88c5\u548c\u8fd0\u8f93<\/strong><\/p>\n

\u5305\u88c5\uff1a25 \u516c\u65a4\/\u7eb8\u677f\u6876<\/p>\n

\u8fd0\u9001\uff1a\u975e\u5371\u9669\u8d27\u7269<\/p>\n

\u50a8\u5b58\u03b2-\u70df\u9170\u80fa\u5355\u6838\u82f7\u9178<\/strong><\/p>\n

\u5b58\u653e\u5728\u5e72\u71e5\u901a\u98ce\u5904\uff0c\u907f\u514d\u9633\u5149\u76f4\u5c04\u3002<\/p>\n

\u7acb\u5373\u8054\u7cfb\u6211\u4eec\uff01<\/b><\/strong><\/h2>\n

\u5982\u679c\u60a8\u9700\u8981\u4ef7\u683c\uff0c\u8bf7\u5728\u4e0b\u8868\u4e2d\u586b\u5199\u60a8\u7684\u8054\u7cfb\u4fe1\u606f\uff0c\u6211\u4eec\u901a\u5e38\u4f1a\u5728 24 \u5c0f\u65f6\u5185\u4e0e\u60a8\u8054\u7cfb\u3002\u60a8\u4e5f\u53ef\u4ee5\u7ed9\u6211\u53d1\u7535\u5b50\u90ae\u4ef6 info@longchangchemical.com<\/span><\/a>\u00a0\u8bf7\u5728\u5de5\u4f5c\u65f6\u95f4\uff08UTC+8 \u5468\u4e00\u81f3\u5468\u516d\uff0c\u4e0a\u5348 8:30 \u81f3\u4e0b\u5348 6:00\uff09\u6216\u4f7f\u7528\u7f51\u7ad9\u5373\u65f6\u804a\u5929\u5de5\u5177\u83b7\u5f97\u53ca\u65f6\u56de\u590d\u3002<\/b><\/strong><\/h4>\n
\n

\u7f3a\u8840\u6027\u8111\u8840\u7ba1\u75c5\u5305\u62ec\u77ed\u6682\u6027\u8111\u7f3a\u8840\u548c\u8111\u6897\u585e\u4e24\u79cd\u7c7b\u578b\u3002\u5176\u4e2d\uff0c\u8111\u6897\u585e\u5728\u4e2d\u533b\u8bca\u65ad\u5b66\u4e0a\u79f0\u4e3a\u7f3a\u8840\u6027\u4e2d\u98ce\uff08IS\uff09\uff0c\u662f\u7531\u4e8e\u5404\u79cd\u539f\u56e0\u9020\u6210\u8111\u7ec4\u7ec7\u5c40\u90e8\u4f9b\u8840\u969c\u788d\uff0c\u5bfc\u81f4\u8111\u7ec4\u7ec7\u7f3a\u8840\u3001\u7f3a\u6c27\u574f\u6b7b\u7684\u4e00\u7cfb\u5217\u795e\u7ecf\u529f\u80fd\u969c\u788d\u3002\u5176\u81f4\u6b7b\u7387\u548c\u81f4\u6b8b\u7387\u9ad8\uff0c\u75c5\u7406\u673a\u5236\u590d\u6742\uff0c\u6bcf\u5e74\u7ed9\u4e16\u754c\u9020\u6210\u5de8\u5927\u7684\u7ecf\u6d4e\u8d1f\u62c5\u3002\u6c27\u8461\u8404\u7cd6\u5265\u593a\uff08OGD\uff09\u662f\u6700\u5e38\u7528\u7684\u4f53\u5916 IS \u6a21\u578b\uff0c\u88ab\u5e7f\u6cdb\u5e94\u7528\u4e8e\u8111\u5352\u4e2d\u7684\u57fa\u7840\u548c\u4e34\u5e8a\u524d\u7814\u7a76\u3002<\/p>\n

\u7ec6\u80de\u81ea\u566c\uff08autophagy\uff09\u5e7f\u6cdb\u5b58\u5728\u4e8e\u771f\u6838\u7ec6\u80de\u4e2d\uff0c\u5728\u7ec6\u80de\u5b58\u6d3b\u548c\u6b7b\u4ea1\u7684\u8c03\u63a7\u4e2d\u53d1\u6325\u7740\u91cd\u8981\u4f5c\u7528\u3002\u5927\u91cf\u7814\u7a76\u8868\u660e\uff0c\u81ea\u566c\u4e0eIS\u7684\u53d1\u751f\u548c\u53d1\u5c55\u5bc6\u5207\u76f8\u5173\u3002\u6709\u7814\u7a76\u8868\u660e\u795e\u7ecf\u5143\u81ea\u566c\u53ef\u51cf\u8f7b\u7f3a\u8840\u6027\u8111\u635f\u4f24\uff0c\u4e5f\u6709\u7814\u7a76\u62a5\u9053\u795e\u7ecf\u5143\u81ea\u566c\u53ef\u52a0\u91cd\u7f3a\u8840\u6027\u8111\u635f\u4f24\uff0c\u4f46\u5177\u4f53\u673a\u5236\u5c1a\u4e0d\u6e05\u695a\u3002
\n\u03b2-\u70df\u9170\u80fa\u5355\u6838\u82f7\u9178\uff08NMN\uff09\u5b58\u5728\u4e8e\u591a\u79cd\u98df\u7269\u4e2d\uff0c\u5b83\u662f\u8c03\u8282\u7ec6\u80de\u8870\u8001\u548c\u7ef4\u6301\u673a\u4f53\u6b63\u5e38\u529f\u80fd\u6240\u5fc5\u9700\u7684\u7269\u8d28\uff0c\u5e76\u53c2\u4e0e\u8bb8\u591a\u91cd\u8981\u7684\u7ec6\u80de\u5185\u4fe1\u53f7\u901a\u8def\u7684\u4f20\u5bfc\u3002\u636e\u62a5\u9053\uff0c\u4f53\u5916\u7ed9\u836f NMN \u53ef\u8fc5\u901f\u5c06 NAD+ \u8f6c\u5316\u4e3a NAD+\uff0c\u8c03\u8282\u7ec6\u80de\u8870\u8001\uff0c\u7ef4\u6301\u673a\u4f53\u6b63\u5e38\u529f\u80fd\u3002NMN \u53ef\u8865\u507f IS \u5bfc\u81f4\u7684 NAD+ \u51cf\u5c11\uff0c\u6539\u5584\u8111\u7f3a\u8840\u795e\u7ecf\u5143\u7684\u635f\u4f24\u3002\u8fd9\u8868\u660e NMN \u5728 IS \u4e2d\u53d1\u6325\u4f5c\u7528\u3002\u4e00\u4e9b\u7814\u7a76\u8868\u660e\uff0cNMN \u53ef\u4fc3\u8fdb\u795e\u7ecf\u8840\u7ba1\u518d\u751f\u3001\u6539\u5584\u8111\u5fae\u8840\u7ba1\u5185\u76ae\u529f\u80fd\u3001\u6297\u708e\u548c\u6297\u51cb\u4ea1\u3002\u4e5f\u6709\u4e00\u4e9b\u7814\u7a76\u8868\u660e\uff0cNMN \u53ef\u901a\u8fc7\u8c03\u8282\u81ea\u566c\u53d1\u6325\u6297\u7f3a\u8840\u6027\u8111\u635f\u4f24\u7684\u4f5c\u7528\uff0c\u4f46 NMN \u8c03\u8282\u81ea\u566c\u6297 IS \u7684\u5177\u4f53\u673a\u5236\u5c1a\u4e0d\u6e05\u695a\u3002<\/p>\n

\u672c\u7814\u7a76\u7684\u76ee\u7684\u662f\u6784\u5efa\u7f3a\u6c27\u7f3a\u7cd6\u7684PC12\u7ec6\u80de\u6a21\u578b\uff0c\u7528MTT\u6cd5\u6d4b\u5b9a\u4f53\u5916\u7ec6\u80de\u5b58\u6d3b\u7387\uff0c\u7528\u900f\u5c04\u7535\u5b50\u663e\u5fae\u955c\u68c0\u6d4b\u81ea\u566c\u4f53\u548c\u81ea\u566c\u6eb6\u9176\u4f53\uff0c\u7528MDC\u89c2\u5bdf\u81ea\u566c\u4f53\u7684\u8367\u5149\u5f3a\u5ea6\uff0c\u68c0\u6d4bLC3-II\/LC3-I\u3001Beclin1\u3001p62\u548cP-mTOR\/mTOR\u81ea\u566c\u76f8\u5173\u56e0\u5b50\u7684\u8868\u8fbe\u3001Western\u5370\u8ff9\u68c0\u6d4bLC3-II\/LC3-I\u3001Beclin1\u3001p62\u548cP-mTOR\/mTOR\u81ea\u566c\u76f8\u5173\u86cb\u767d\u7684\u8868\u8fbe\uff0c\u4ee5\u660e\u786eNMN\u5bf9OGD\u8bf1\u5bfc\u7684PC12\u7ec6\u80de\u81ea\u566c\u635f\u4f24\u7684\u5f71\u54cd\u3002<\/p>\n

2017 \u5e74\u300a\u67f3\u53f6\u5200\u300b\u7814\u7a76\u663e\u793a\uff0c\u8111\u5352\u4e2d\u662f\u9020\u6210\u4e2d\u56fd\u4eba\u5bff\u547d\u635f\u5931\u5e74\u6570\u7684\u4e3b\u8981\u75be\u75c5\uff0c\u5177\u6709\u8fdb\u5c55\u5feb\u3001\u81f4\u6b7b\u7387\u9ad8\u3001\u81f4\u6b8b\u7387\u9ad8\u7b49\u7279\u70b9\u3002\u5176\u4e2d\uff0cIS\u5360\u8111\u5352\u4e2d\u603b\u6570\u768460%\u81f370%\uff0cIS\u662f\u7531\u4e8e\u8840\u7ba1\u5835\u585e\u5bfc\u81f4\u8111\u90e8\u67d0\u4e00\u533a\u57df\u4f9b\u8840\u51cf\u5c11\u5f15\u8d77\u7684\u3002\u8111\u7ec4\u7ec7\u7f3a\u8840\u7f3a\u6c27\u4f1a\u5f15\u53d1\u4e00\u7cfb\u5217\u75c5\u7406\u751f\u7406\u53cd\u5e94\uff0c\u5982\u7ec6\u80de\u81ea\u566c\u3001\u51cb\u4ea1\u3001\u6c27\u5316\u5e94\u6fc0\u3001\u7ec6\u80de\u5185\u9499\u8d85\u8f7d\u7b49\u3002IS \u5e78\u5b58\u8005\u7684\u5eb7\u590d\u5468\u671f\u8f83\u957f\uff0c\u589e\u52a0\u4e86\u5168\u7403\u7684\u7ecf\u6d4e\u8d1f\u62c5\u3002\u76ee\u524d\uff0c\u5e02\u573a\u4e0a\u7528\u4e8e\u6cbb\u7597 IS \u7684\u836f\u7269\u6709\u8bb8\u591a\u7981\u5fcc\u75c7\u3002\u56e0\u6b64\uff0c\u6709\u5fc5\u8981\u4e0d\u65ad\u63a2\u7d22\u9884\u9632\u548c\u6cbb\u7597 IS \u7684\u836f\u7269\u3002OGD \u662f\u4f53\u5916\u7814\u7a76 IS \u7684\u7ecf\u5178\u6a21\u578b\uff0c\u800c PC12 \u7ec6\u80de\u7cfb\u662f\u7814\u7a76\u795e\u7ecf\u5143\u635f\u4f24\u6700\u5e38\u7528\u7684\u7ec6\u80de\u7cfb\u4e4b\u4e00\uff0c\u5e38\u7528\u4e8e\u7f3a\u8840\u7f3a\u6c27\u635f\u4f24\u7684\u7814\u7a76\u3002\u56e0\u6b64\uff0c\u672c\u5b9e\u9a8c\u91c7\u7528 OGD PC12 \u7ec6\u80de\u6a21\u578b\u8fdb\u884c\u4f53\u5916\u7814\u7a76\u3002<\/p>\n

NMN \u662f\u4e00\u79cd\u5b58\u5728\u4e8e\u4eba\u4f53\u548c\u8bb8\u591a\u98df\u7269\u4e2d\u7684\u5929\u7136\u7269\u8d28\uff0c\u5206\u5b50\u91cf\u4e3a 334.22\u3002\u5b83\u662f\u70df\u9170\u80fa-\u78f7\u9178\u6838\u7cd6\u8f6c\u79fb\u9176\u53cd\u5e94\u7684\u4ea7\u7269\uff0c\u4e5f\u662f NAD+ \u7684\u4e3b\u8981\u524d\u4f53\u4e4b\u4e00\u3002\u6709\u7814\u7a76\u53d1\u73b0\uff0c\u901a\u8fc7\u8c03\u8282\u751f\u7269\u4f53\u5185\u7684 NMN \u6c34\u5e73\uff0c\u5bf9\u5fc3\u8111\u8840\u7ba1\u75be\u75c5\u3001\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u548c\u8870\u8001\u9000\u5316\u6027\u75be\u75c5\u6709\u8f83\u597d\u7684\u6cbb\u7597\u548c\u6062\u590d\u4f5c\u7528\u3002\u53e6\u636e\u62a5\u9053\uff0c\u5728\u5927\u9f20 MCAO \u6a21\u578b\u4e2d\uff0c\u670d\u7528 NMN \u53ef\u51cf\u5c11\u6897\u6b7b\u9762\u79ef\u548c\u795e\u7ecf\u529f\u80fd\u635f\u4f24\u3002\u5728\u672c\u5b9e\u9a8c\u4e2d\uff0c\u901a\u8fc7 MTT \u8bc1\u660e OGD \u53ef\u964d\u4f4e PC12 \u7ec6\u80de\u7684\u5b58\u6d3b\u7387\uff0c\u800c\u6d53\u5ea6\u4e3a 400\u3001800 \u548c 1600 \u03bcmol\/L \u7684 NMN \u53ef\u63d0\u9ad8 OGD PC12 \u7ec6\u80de\u7684\u5b58\u6d3b\u7387\uff0c\u5176\u4e2d 800 \u03bcmol\/L \u6d53\u5ea6\u7684\u5b58\u6d3b\u7387\u6700\u9ad8\uff1b\u800c\u6d53\u5ea6\u4e3a 200 \u548c 3200 \u03bcmol\/L \u7684 NMN \u7ec6\u80de\u5b58\u6d3b\u7387\u65e0\u663e\u8457\u5dee\u5f02\uff0c\u8fd9\u8868\u660e 200 \u03bcmol\/L \u6d53\u5ea6\u7684 NMN \u53ef\u63d0\u9ad8 PC12 \u7ec6\u80de\u7684\u5b58\u6d3b\u7387\u3002\u8fd9\u8868\u660e 200 \u03bcmol\/L \u7684\u6d53\u5ea6\u8fd8\u4e0d\u662f\u63d0\u9ad8 OGD \u8bf1\u5bfc\u7684 PC12 \u7ec6\u80de\u5b58\u6d3b\u7387\u7684\u6709\u6548\u6d53\u5ea6\uff0c\u800c 3200 \u03bcmol\/L \u7684\u6d53\u5ea6\u53ef\u80fd\u8fc7\u9ad8\uff0c\u53ef\u80fd\u4f1a\u5bf9\u7ec6\u80de\u672c\u8eab\u9020\u6210\u4e00\u5b9a\u7684\u635f\u4f24\u3002<\/p>\n

\u7ec6\u80de\u81ea\u566c\u88ab\u79f0\u4e3aII\u578b\u7a0b\u5e8f\u6027\u7ec6\u80de\u6b7b\u4ea1\uff0c\u662f\u7ec6\u80de\u5728\u81ea\u566c\u76f8\u5173\u57fa\u56e0\u7684\u8c03\u63a7\u4e0b\uff0c\u5229\u7528\u6eb6\u9176\u4f53\u964d\u89e3\u81ea\u8eab\u53d7\u635f\u3001\u53d8\u6027\u6216\u8870\u8001\u7684\u5927\u5206\u5b50\u548c\u7ec6\u80de\u5668\uff0c\u4ee5\u7ef4\u6301\u7ec6\u80de\u751f\u5b58\u3001\u5206\u5316\u3001\u751f\u957f\u548c\u7a33\u5b9a\u7684\u8fc7\u7a0b\u3002\u7814\u7a76\u8868\u663e\u793a\uff0cIS\u53d1\u751f\u540e\u4f1a\u8bf1\u5bfc\u81ea\u566c\uff0c\u540c\u65f6\u81ea\u566c\u4e5f\u4f34\u968f\u7740IS\u75c5\u7406\u8fc7\u7a0b\u7684\u53d1\u5c55\uff0c\u5728IS\u7684\u6025\u6027\u671f\u3001\u4e9a\u6025\u6027\u671f\u3001\u6062\u590d\u671f\u548c\u540e\u9057\u75c7\u671f\u56db\u4e2a\u9636\u6bb5\u53d1\u6325\u4e0d\u540c\u7684\u8c03\u63a7\u4f5c\u7528\u3002<\/p>\n

mTORCl\u5bf9\u96f7\u5e15\u9709\u7d20\u654f\u611f\uff0c\u8d1f\u8d23\u6574\u5408\u751f\u957f\u56e0\u5b50\u548c\u8425\u517b\u4fe1\u53f7\uff0c\u4e3b\u8981\u8c03\u63a7\u7ec6\u80de\u81ea\u566c\u3001\u6838\u7cd6\u4f53\u751f\u7269\u53d1\u751f\u3001\u86cb\u767d\u8d28\u7ffb\u8bd1\u548c\u8102\u8d28\u5408\u6210\uff0cmTORT\u88ab\u8ba4\u4e3a\u662f\u81ea\u566c\u7684\u9600\u95e8\u3002\u7814\u7a76\u8868\u660e\uff0c\u78f7\u9178\u5316\u7684 mTOR \u53ef\u4ee5\u51cf\u8f7b\u6c27\u7cd6\u5265\u593a\u635f\u4f24\uff0c\u8d77\u5230\u4fdd\u62a4\u7ec6\u80de\u7684\u4f5c\u7528\u30023-MA \u662f\u4e00\u79cd\u5e38\u7528\u7684\u81ea\u566c\u6291\u5236\u5242\uff0crAPA \u662f\u4e00\u79cd mTOR \u6291\u5236\u5242\uff0c\u5b83\u901a\u8fc7\u6291\u5236 mTORC1 \u6765\u8bf1\u5bfc\u81ea\u566c\u7684\u53d1\u751f\uff0c\u4e5f\u88ab\u79f0\u4e3a\u81ea\u566c\u6fc0\u6d3b\u5242\u3002\u672c\u5b9e\u9a8c\u8bbe\u7f6e\u4e86 3-MA \u548c RAPA \u7ec4\u6765\u5e72\u9884 PC12 \u7ec6\u80de\u4e2d\u7531 OGD \u8bf1\u5bfc\u7684\u81ea\u566c\u7684\u8c03\u63a7\uff0c\u8fd8\u8bbe\u7f6e\u4e86 3-MA\u3001RAPA \u548c\u836f\u7269\u7ec4\u5408\u7ec4\u6765\u89c2\u5bdf NMN \u662f\u5426\u80fd\u62b5\u6d88 3-MA \u6216 RAPA \u5bf9 PC12 \u7ec6\u80de\u4e2d\u7531 OGD \u8bf1\u5bfc\u7684\u81ea\u566c\u7684\u5f71\u54cd\u3002<\/p>\n

Beclin1\u662f\u4e00\u79cd\u516c\u8ba4\u7684\u81ea\u566c\u8c03\u8282\u56e0\u5b50\uff0c\u4e0e\u81ea\u566c\u5448\u6b63\u76f8\u5173\u3002Beclin1\u4e0eVPS15\u3001VPS34\u548cATG14\u7b49\u86cb\u767d\u76f8\u4e92\u4f5c\u7528\uff0c\u53d1\u6325\u81ea\u566c\u548c\u819c\u8f6c\u8fd0\u7684\u529f\u80fd\u3002LC3\u662f\u9175\u6bcd\u4e2d\u6cdb\u7d20\u6837\u4fee\u9970\u7269ATG8\u7684\u540c\u6e90\u7269\uff0c\u88ab\u8ba4\u4e3a\u5728\u81ea\u566c\u4e2d\u53d1\u6325\u4f5c\u7528\u3002\u7ecf ATG4 \u5904\u7406\u540e\uff0cLC3 \u5931\u53bb\u5176 C \u7aef\u6b8b\u57fa\uff0c\u5e76\u8f6c\u5316\u4e3a LC3-I\u3002LC3-I \u7ecf\u5386\u4e00\u8fde\u4e32\u7c7b\u4f3c\u6cdb\u7d20\u5316\u7684\u9176\u4fc3\u53cd\u5e94\uff0c\u4e0e\u81ea\u566c\u4f53\u819c\u4e0a\u7684\u8102\u8d28\u5206\u5b50\u78f7\u8102\u9170\u4e59\u9187\u80fa\u5171\u4ef7\u8fde\u63a5\uff0c\u5e76\u8f6c\u5316\u4e3a LC3-II\uff0cLC3-II \u4e0e LC3-I \u7684\u6bd4\u7387\u589e\u52a0\u8868\u660e\u81ea\u566c\u6c34\u5e73\u5347\u9ad8\u3002p62 \u662f\u53cd\u6620\u81ea\u566c\u6d3b\u6027\u7684\u6807\u5fd7\u86cb\u767d\uff0c\u5176\u86cb\u767d\u6c34\u5e73\u4e0e\u81ea\u566c\u6c34\u5e73\u76f8\u5173\u3001\u5f53\u81ea\u566c\u53d1\u751f\u65f6\uff0cp62 \u86cb\u767d\u4f1a\u5728\u7ec6\u80de\u8d28\u4e2d\u964d\u89e3\uff1b\u5f53\u81ea\u566c\u6d3b\u6027\u51cf\u5f31\u3001\u81ea\u566c\u529f\u80fd\u7f3a\u9677\u65f6\uff0cp62 \u86cb\u767d\u4f1a\u5728\u7ec6\u80de\u8d28\u4e2d\u79ef\u7d2f\u3002\u672c\u5b9e\u9a8c\u901a\u8fc7 Western \u5370\u8ff9\u8bc1\u5b9e\uff0cNMN \u53ef\u4e0b\u8c03 Beclin1 \u548c LC3-II\/LC3-I \u86cb\u767d\u7684\u76f8\u5bf9\u8868\u8fbe\uff0c\u4e0a\u8c03 P-mTOR\/mTOR \u548c p62 \u86cb\u767d\u7684\u8868\u8fbe\u3002\u6b64\u5916\uff0c\u900f\u5c04\u7535\u955c\u548c MDC \u6cd5\u4e5f\u8bc1\u5b9e\u4e86 NMN \u80fd\u51cf\u5c11 OGD PC12 \u7ec6\u80de\u4e2d\u81ea\u566c\u6ce1\u7684\u6570\u91cf\u3001\u81ea\u566c\u6eb6\u9176\u4f53\u7684\u6570\u91cf\u548c\u8367\u5149\u6591\u70b9\u53ca\u5f3a\u5ea6\u3002\u4ee5\u4e0a\u7ed3\u679c\u8868\u660e\uff0cNMN \u53ef\u6291\u5236 PC12 \u7ec6\u80de\u7531 OGD \u8bf1\u5bfc\u7684\u81ea\u566c\u3002
\n\u7efc\u4e0a\u6240\u8ff0\uff0c\u4e00\u5b9a\u5242\u91cf\u7684 NMN \u53ef\u6297 OGD \u8bf1\u5bfc\u7684 PC12 \u7ec6\u80de\u81ea\u566c\u635f\u4f24\uff0c\u4ece\u800c\u53d1\u6325\u7ec6\u80de\u4fdd\u62a4\u4f5c\u7528\uff0c\u800c\u8fd9\u79cd\u4fdd\u62a4\u4f5c\u7528\u53ef\u80fd\u4e0e mTOR \u76f8\u5173\u901a\u8def\u6709\u5173\u3002\u672c\u7814\u7a76\u53ef\u4e3a NMN \u9884\u9632 OGD \u8bf1\u5bfc\u7684\u7ec6\u80de\u81ea\u566c\u635f\u4f24\u63d0\u4f9b\u4e00\u5b9a\u7684\u9776\u70b9\u53c2\u8003\uff0c\u4e3a\u5929\u7136\u5316\u5408\u7269 NMN \u7684\u5f00\u53d1\u79ef\u7d2f\u4e00\u5b9a\u7684\u5b9e\u9a8c\u6570\u636e\u3002<\/p>","protected":false},"excerpt":{"rendered":"

\u5316\u5b66\u540d\u79f0\u03b2-\u70df\u9170\u80fa\u5355\u6838\u82f7\u9178<\/p>\n

\u5316\u5b66\u6587\u6458\u793e\u7f16\u53f7\uff1a1094-61-7<\/p>\n

\u5206\u5b50\u5f0f\uff1a C11H15N2O8PC11H15N2O8P<\/p>\n

\u5206\u5b50\u91cf\uff1a334.22<\/p>\n

\u5916\u89c2\u767d\u8272\u7c89\u672b<\/p>\n

Assay:97%~100.0%<\/p>","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[113],"product_tag":[],"class_list":{"0":"post-6829","1":"product","2":"type-product","3":"status-publish","5":"product_cat-organic-intermediate","7":"first","8":"instock","9":"shipping-taxable","10":"product-type-simple"},"yoast_head":"\nChina beta-nicotinamide mononucleotide Manufacturer CAS 1094-61-7 - Longchang Chemical<\/title>\n<meta name=\"description\" content=\"beta-nicotinamide mononucleotide CAS 1094-61-7 Organic Intermediate is an organic intermediate for chemical synthesis and formulation manufacturing.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangchemical.com\/zh\/product\/beta-nicotinamide-mononucleotide-cas-1094-61-7\/\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"China beta-nicotinamide mononucleotide Manufacturer CAS 1094-61-7 - 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