2-丁基-4-氯-5-甲酰基咪唑 CAS 83857-96-9

产品名称2-丁基-4-氯-5-甲酰基咪唑

CAS: 83857-96-9

分子式C8H11ClN2O

分子量: 186.64

2-Butyl-4-chloro-5-formylimidazole Structure(2-丁基-4-氯-5-甲酰基咪唑结构):2-丁基-4-氯-5-甲酰基咪唑的结构

外观淡黄色结晶粉末

纯度:98.0%~101.0%

应用场景

1. Pharmaceutical Synthesis Intermediates (Main Applications)
This is the most core and clearly defined industrial use of this compound.

Antihypertensive Drug Synthesis: It is a key intermediate in the synthesis of angiotensin II receptor antagonists (sartan drugs).

Losartan: It is a key synthetic intermediate for losartan.

Satan Drugs: It is generally widely classified as a common intermediate for sartan drugs.

Other Drug Related Applications: According to patent information, it can be used as an intermediate or starting material for the synthesis of other bioactive compounds (such as glucagon receptor modulators).

2. Biomedical Research Applications
These applications are currently mostly in the laboratory research stage.

Antibacterial and Anticancer Activity Studies:

Metal complexes of its derivatives (such as thiourea and Schiff bases) have shown antibacterial activity against some Gram-positive and Gram-negative bacteria in studies.

Metal complexes of some derivatives (such as Cu(II) and Ni(II) complexes) have shown anticancer activity against the breast cancer cell line (MDA-MB 231) in in vitro studies.

Enzyme Inhibitor Research: Studies have used its derivatives to design and synthesize novel peptides and evaluate their potential as angiotensin-converting enzyme inhibitors.

3. Materials Science Applications
Corrosion Inhibitors: Its derivatives (such as Schiff bases) have been explored as metal corrosion inhibitors in laboratory studies. For example, studies have shown that they inhibit the corrosion of low-carbon steel in acidic media.

4. Chemical Synthesis and Industrial Applications
General Organic Synthesis Building Blocks: Due to their unique chemical structure (containing both chlorine and aldehyde groups), they can serve as important organic synthesis intermediates for constructing more complex heterocyclic compounds or functional molecules.

Agrochemical Development: Patent information shows that molecules containing this compound’s structural units are being developed as potential fungicides and plant growth regulators.

描述

2-丁基-4-氯-5-甲酰基咪唑 CAS 83857-96-9

测试项目 规格
外观 少许 - 黄色结晶粉末
纯净 98.0%~101.0%
PAA 的内容 1%max
业连管的内容 1%max
最大单一未知杂质 0.5%max
杂质总量 1%max
体积密度 g/cm 1.03~1.10

2-丁基-4-氯-5-甲酰基咪唑的用途

2-Butyl-4-chloro-5-formylimidazole 可用作洛沙坦的降压药。

 

2-丁基-4-氯-5-甲酰基咪唑包

25 公斤/纤维桶。

 

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