{"id":3447,"date":"2020-12-07T13:00:32","date_gmt":"2020-12-07T13:00:32","guid":{"rendered":"https:\/\/longchangchemical.com\/?post_type=product&p=3447"},"modified":"2025-12-23T04:02:30","modified_gmt":"2025-12-23T04:02:30","slug":"probenecid-cas-57-66-9","status":"publish","type":"product","link":"https:\/\/longchangchemical.com\/tr\/product\/probenecid-cas-57-66-9\/","title":{"rendered":"Probenesid CAS 57-66-9"},"content":{"rendered":"

Probenesid nedir?<\/strong><\/h2>\n

 <\/p>\n

\n

1. Probenesid, y\u00fcksek etkili penisilin ve sefalosporin antibiyotiklerin yeni bir t\u00fcr\u00fcd\u00fcr. \u00d6zellikle penisilinler, sefalosporin antibiyotikler sinerjisti i\u00e7in kullan\u0131l\u0131r, sefalosporinlerin, penisilinlerin etkinli\u011fini 8-10 kat art\u0131rabilir.<\/h4>\n

2. Ayr\u0131ca, bu \u00fcr\u00fcn b\u00f6brek t\u00fcb\u00fcllerinde zay\u0131f organik asitlerin (penisilin, sefalosporin gibi) salg\u0131lanmas\u0131n\u0131 rekabet\u00e7i bir \u015fekilde inhibe edebilir, b\u00f6ylece bu antibiyotiklerin kan konsantrasyonunu art\u0131rabilir ve etki s\u00fcrelerini uzatabilir.<\/h4>\n

3. Bu \u00fcr\u00fcn oral uygulama ile kolayca emilir ve plazma protein ba\u011flanma oran\u0131 85% ila 90% kadar y\u00fcksektir. Yeti\u015fkinler her seferinde 1 g al\u0131r, plazma konsantrasyonu 2 ila 4 saat i\u00e7inde zirveye ula\u015f\u0131r ve yar\u0131lanma \u00f6mr\u00fc 6 ila 12 saattir. Probenesid karaci\u011ferde h\u0131zla metabolize olur ve ana metaboliti probenesid asetoglukuronik asittir. Metabolitler esas olarak idrarla at\u0131l\u0131r. Bu \u00fcr\u00fcn\u00fcn anti-enflamatuar ve analjezik etkileri yoktur, bu nedenle akut gut hastal\u0131\u011f\u0131na kar\u015f\u0131 etkisizdir.<\/h4>\n

Probenesid Kullan\u0131m\u0131<\/strong><\/h2>\n
<\/div>\n

1. Gut, hiper\u00fcrisemi tedavisi, at ba\u015f\u0131na 1.25-2.5g, inek, koyun, domuz 0.5g, tavuk 40mg, kedi, k\u00f6pek 60mg, g\u00fcnde iki kez.<\/h4>\n

2. Penisilin, sefalosporin etkinli\u011fini ve etki s\u00fcresini artt\u0131rmak i\u00e7in, 1 k\u0131s\u0131m probeneside g\u00f6re (saf \u00fcr\u00fcn olarak hesaplan\u0131r): 3.5 k\u0131s\u0131m penisilin, sefalosporin oran\u0131 uyumlulu\u011fu.<\/h4>\n
<\/div>\n
<\/div>\n

Probenecid Talimatlar\u0131<\/strong><\/h2>\n
<\/div>\n

\u00dcr\u00fcn su ilave edilerek \u00e7\u00f6z\u00fcld\u00fckten sonra (\u00e7\u00f6z\u00fcnme oran\u0131 fiili duruma g\u00f6re belirlenebilir), seyreltik sodyum hidroksit \u00e7\u00f6zeltisinde \u00e7\u00f6z\u00fcn\u00fcr ve seyreltik asitte neredeyse \u00e7\u00f6z\u00fcnmez.<\/h4>\n
<\/div>\n

Probenesid Ambalajlama, depolama, ta\u015f\u0131ma ve son kullanma tarihi<\/strong><\/h2>\n
<\/div>\n

\u00dcr\u00fcn m\u00fc\u015fterinin ihtiyac\u0131na g\u00f6re 1kg, 5kg, 10kg, 20kg olarak paketlenebilir veya kullan\u0131c\u0131n\u0131n ihtiyac\u0131na g\u00f6re paketlenebilir; karanl\u0131k, kuru ve kapal\u0131 bir yerde saklanabilir ve ge\u00e7erlilik s\u00fcresi 24 ayd\u0131r.<\/h4>\n

 <\/p>\n<\/div>\n

\u015eimdi Bize Ula\u015f\u0131n!<\/b><\/strong><\/h2>\n

COA, MSDS veya TDS'ye ihtiyac\u0131n\u0131z varsa, l\u00fctfen a\u015fa\u011f\u0131daki forma ileti\u015fim bilgilerinizi girin, genellikle 24 saat i\u00e7inde sizinle ileti\u015fime ge\u00e7ece\u011fiz. Bana e-posta da g\u00f6nderebilirsiniz info@longchangchemical.com<\/a><\/span> \u00c7al\u0131\u015fma saatleri i\u00e7inde (8:30 - 6:00 UTC+8 Pzt.~Sat.) veya h\u0131zl\u0131 yan\u0131t almak i\u00e7in web sitesi canl\u0131 sohbetini kullan\u0131n.<\/b><\/strong><\/h4>","protected":false},"excerpt":{"rendered":"

Probenesid CAS 57-66-9<\/strong><\/h1>\n

Kimyasal Ad\u0131: Probenesid<\/h4>\n

CAS numaras\u0131: 57-66-9<\/h4>\n

Molek\u00fcler form\u00fcl: C13H19NO4S<\/h4>\n

Molek\u00fcl a\u011f\u0131rl\u0131\u011f\u0131: 285,36<\/h4>\n

G\u00f6r\u00fcn\u00fc\u015f: beyaz kristal toz<\/h4>\n

Etkili i\u00e7erik (%): \u226595-99<\/h4>\n

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