{"id":6882,"date":"2024-04-29T03:44:48","date_gmt":"2024-04-29T03:44:48","guid":{"rendered":"https:\/\/longchangchemical.com\/?p=6882"},"modified":"2024-04-29T03:44:48","modified_gmt":"2024-04-29T03:44:48","slug":"what-is-the-difference-between-chitin-chitosan-and-chitosan","status":"publish","type":"post","link":"https:\/\/longchangchemical.com\/tr\/what-is-the-difference-between-chitin-chitosan-and-chitosan\/","title":{"rendered":"Kitin, kitosan ve kitosan aras\u0131ndaki fark nedir?"},"content":{"rendered":"

Kitin, kitosan<\/a> ve kitooligosakkaritlerin hepsi kabuklular\u0131n (\u00f6rne\u011fin karidesler, yenge\u00e7ler, kabuklu deniz hayvanlar\u0131) kabuklar\u0131ndan elde edilen polisakkaritlerdir ve yap\u0131 ve kullan\u0131m a\u00e7\u0131s\u0131ndan baz\u0131 farkl\u0131l\u0131klar\u0131 vard\u0131r:<\/p>\n

1. Kitin (Kitosan):
\nKitin, \u03b2-1,4-glikozidik ba\u011flarla ba\u011flanm\u0131\u015f N-asetilglukozamin monomerlerinden olu\u015fan do\u011frusal bir polisakkarittir.
\nKabuklular\u0131n d\u0131\u015f iskeletinin \u00f6nemli bir bile\u015fenidir ve mantarlar\u0131n h\u00fccre duvarlar\u0131nda da bulunur.
\nKitin sert ve dayan\u0131kl\u0131 \u00f6zelliklere sahiptir ve genellikle biyot\u0131p, g\u0131da end\u00fcstrisi ve tar\u0131mda kullan\u0131l\u0131r.
\n2. Kitosan (Chitosan):
\nKitosan, kitinin deasetilasyonu ile elde edilen bir \u00fcr\u00fcnd\u00fcr, yani kitinin asetil k\u0131sm\u0131 uzakla\u015ft\u0131r\u0131larak kitosan olu\u015fturulur.
\nKitosan, glukozamin birimleri ve art\u0131k asetil glukozamin birimlerinden olu\u015fan do\u011frusal bir polimerdir.
\n\u0130yi biyouyumluluk, bozunabilirlik, antimikrobiyal \u00f6zellikler vb. gibi \u00e7e\u015fitli \u00f6zelliklere sahiptir. Bu nedenle t\u0131p, g\u0131da ve kozmetik alanlar\u0131nda geni\u015f bir uygulama alan\u0131na sahiptir.
\n3. Kitooligosakkaritler (COS):
\nKitooligosakkaritler, genellikle 2 ila 10 glukozamin biriminden olu\u015fan kitosan\u0131n enzimatik veya asit hidrolizi ile elde edilen oligosakkarit benzeri \u00fcr\u00fcnlerdir.
\nKitosandan daha k\u00fc\u00e7\u00fck bir molek\u00fcler a\u011f\u0131rl\u0131\u011fa ve daha aktif fonksiyonel gruplara sahiptir, bu da daha iyi biyolojik aktivite ve biyoyararlan\u0131m sa\u011flar.
\nKitosan\u0131n antibakteriyel, antioksidan, antit\u00fcm\u00f6r ve di\u011fer biyolojik aktivitelere sahip oldu\u011fu d\u00fc\u015f\u00fcn\u00fclmektedir ve farmas\u00f6tikler ve nutras\u00f6tikler alan\u0131nda b\u00fcy\u00fck ilgi g\u00f6rm\u00fc\u015ft\u00fcr.
\nBu nedenle, kitin, kitosan ve kito-oligosakkaritlerin hepsi kabuklu organizmalar\u0131n kabuklar\u0131ndan elde edilen polisakkaritler olmas\u0131na ra\u011fmen, yap\u0131lar\u0131 ve \u00f6zellikleri ve dolay\u0131s\u0131yla uygulamalar\u0131 bak\u0131m\u0131ndan farkl\u0131l\u0131k g\u00f6sterirler.<\/p>\n

Kitin, v\u00fccudun ba\u011f\u0131\u015f\u0131kl\u0131k fonksiyonunu \u00f6nemli \u00f6l\u00e7\u00fcde ve kapsaml\u0131 bir \u015fekilde iyile\u015ftirme etkisine sahiptir.
\nBu nedenle, \u00e7e\u015fitli vir\u00fcsler, bakteriler, parazitler ve hatta kanser kar\u015f\u0131s\u0131nda, insan v\u00fccudundaki ba\u011f\u0131\u015f\u0131kl\u0131k fonksiyonu herhangi bir zamanda aktive edilebildi\u011fi s\u00fcrece, istilac\u0131lara etkili bir \u015fekilde direnebilir. Kitosan daha y\u00fcksek protein adsorpsiyon kapasitesine sahiptir; Kitosan, her t\u00fcrl\u00fc t\u00fcrevin \u00fcretimi i\u00e7in uygun afinite ve \u00e7\u00f6z\u00fcn\u00fcrl\u00fc\u011fe sahiptir; Kitosan, di\u011fer yararl\u0131 bakterilerin b\u00fcy\u00fcmesini etkilemezken, oral streptokoklar\u0131n b\u00fcy\u00fcmesini se\u00e7ici ve y\u00fcksek oranda inhibe eder. H\u00fccreleri onarma, h\u00fccreleri ind\u00fckleme ve h\u00fccreleri aktive etme, h\u00fccre zar\u0131 onar\u0131m\u0131ndan h\u00fccre zar\u0131n\u0131 onarabilir, h\u00fccre sa\u011fl\u0131kl\u0131 olduktan sonra h\u00fccre zar\u0131 onar\u0131m\u0131, h\u00fccre aktive edilir, bu nedenle kitosan h\u00fccreleri aktive etme i\u015flevine sahiptir.<\/p>\n

\u0130kinci olarak, kitin anti-t\u00fcm\u00f6r etkiye sahiptir.
\nPozitif y\u00fckl\u00fc bir polikasyon elektroliti olan kitin, t\u00fcm\u00f6r h\u00fccrelerinin y\u00fczeyine adsorbe olabilir ve ba\u011f\u0131\u015f\u0131kl\u0131k sistemini aktive ederek t\u00fcm\u00f6r h\u00fccrelerinin b\u00fcy\u00fcmesini ve metastaz\u0131n\u0131 engelleyici bir rol oynayabilir. Hepimizin bildi\u011fi gibi, karsinotoksinler serum demirinde d\u00fc\u015f\u00fc\u015fe neden olur ve demirdeki d\u00fc\u015f\u00fc\u015f anemiye yol a\u00e7ar. Ayr\u0131ca, kanser toksini tokluk sinirinin uyar\u0131lmas\u0131na ve v\u00fccut ya\u011f\u0131n\u0131n ayr\u0131\u015fmas\u0131na yol a\u00e7arak i\u015ftah\u0131n azalmas\u0131na neden olur, bu da hastan\u0131n kemik incelmesine ve a\u011fr\u0131ya neden olur. Kitosan kanser toksinini inhibe edebilir, b\u00f6ylece kanser sar\u0131s\u0131 insanlar anemik olmaz ve i\u015ftah \u00e7ok iyidir, kanser hastalar\u0131na a\u011fr\u0131y\u0131 hafifletmek i\u00e7in. Genellikle kanser hastalar\u0131n\u0131n v\u00fccut s\u0131v\u0131lar\u0131 asitlenirken, kitin t\u00fckettikten sonra v\u00fccut s\u0131v\u0131lar\u0131 zay\u0131f alkali olacak ve fagositler v\u00fccut s\u0131v\u0131lar\u0131n\u0131n sonunda PH de\u011feri 7.4 civar\u0131nda aktif olacak ve bu da \u00e7ok say\u0131da kanser h\u00fccresini yutabilecektir.<\/p>\n

Japon onkolog Profes\u00f6r Togura, 20 y\u0131l \u00f6nce kanser h\u00fccrelerinin kendilerinin metastaz yapamad\u0131\u011f\u0131n\u0131 ve ancak negatif y\u00fckl\u00fc bir sonraki molek\u00fclle birle\u015ferek metastaz yapabildi\u011fini, kitinin ise katyonik yenilebilir bir lif oldu\u011funu ve pozitif y\u00fckl\u00fc oldu\u011funu, dolay\u0131s\u0131yla bir sonraki molek\u00fclle birle\u015febildi\u011fini, bunun da kanser h\u00fccrelerinin bir sonraki molek\u00fclle birle\u015fmesini engelledi\u011fini ve b\u00f6ylece kanser h\u00fccrelerinin metastaz\u0131n\u0131 etkili bir \u015fekilde engelledi\u011fini geli\u015ftirmi\u015f ve ke\u015ffetmi\u015ftir.<\/p>\n

On y\u0131l \u00f6nce, bir kitin akademik seminerinde bir profes\u00f6r, Japonya'da, kitin bir enjeksiyon olarak yap\u0131lm\u0131\u015ft\u0131r - uzun y\u0131llard\u0131r kullan\u0131lan kanser h\u00fccresi metastaz\u0131n\u0131 inhibe eder, ancak genel halk kullanmay\u0131 g\u00f6ze alamaz, bir enjeksiyon 10.000 ABD dolar\u0131na mal olacak, her g\u00fcn \u00fc\u00e7 enjeksiyon, \u00fc\u00e7 ard\u0131\u015f\u0131k ay tedavi edilebilir. Bununla birlikte, kaps\u00fcl insanlar\u0131n yemeye g\u00fcc\u00fc yetebilir, \u00f6zellikle sa\u011fl\u0131k hizmetlerinin miktar\u0131 daha ucuzdur, g\u00fcnde sadece iki dolar.<\/p>\n

\u00dc\u00e7\u00fcnc\u00fc olarak, kitin kan \u015fekerini d\u00fczenleyebilir, diyabet tedavisine yard\u0131mc\u0131 olabilir.
\nKitin g\u00fc\u00e7l\u00fc bir adsorpsiyon etkisine sahiptir, fazla \u015fekeri adsorbe edebilir ve v\u00fccuttan d\u0131\u015far\u0131 atabilir. Kitin asit-baz dengesini d\u00fczenleyebilir, b\u00f6ylece pankreas adac\u0131k dokusunun \u00f6demi, dejenerasyonu, fibrozisi onar\u0131l\u0131r. Diyabet hastalar\u0131 en \u00e7ok kan glikozundan endi\u015fe duyarlar, ancak diyabetle do\u011frudan ili\u015fkili olan kandaki glikozdur, t\u00fcm \u015fekerler de\u011fil. Kitosan\u0131n metabolik par\u00e7alanma \u00fcr\u00fcn\u00fc olan glukozamin, pankreatik beta h\u00fccrelerini do\u011frudan aktive edebilir, pankreatik beta h\u00fccrelerinin say\u0131s\u0131n\u0131 ve i\u015flevini art\u0131rabilir ve pankreatik i\u015flevi geri kazand\u0131rabilir. Asidik v\u00fccut, ba\u015fta diyabet olmak \u00fczere \u00e7e\u015fitli hastal\u0131klara neden olan su\u00e7ludur. Deneyler, insan v\u00fccut s\u0131v\u0131lar\u0131n\u0131n PH de\u011ferindeki her 0,1'lik art\u0131\u015f i\u00e7in ins\u00fclin aktivitesinin 30% artaca\u011f\u0131n\u0131 kan\u0131tlam\u0131\u015ft\u0131r. Kitosan, insan v\u00fccudunun PH de\u011ferini y\u00fckseltebilen, insan sa\u011fl\u0131\u011f\u0131 i\u00e7in faydal\u0131 olan zay\u0131f bir alkali sunan alkali bir polisakkarittir. Kitosan, g\u0131dalardaki fazla \u015fekeri adsorbe edebilen ve v\u00fccuttan d\u0131\u015far\u0131 atarak kan \u015fekerinin y\u00fckselmesini \u00f6nleyen g\u00fc\u00e7l\u00fc bir adsorpsiyon etkisine sahiptir. Ayn\u0131 zamanda, kitosan diyabetin komplikasyonlar\u0131n\u0131 \u00f6nleyebilir ve iyile\u015ftirebilir ve katarakt, retina dejenerasyonu ve fundopati insidans\u0131n\u0131 azaltabilir.<\/p>\n

D\u00f6rd\u00fcnc\u00fc olarak, kitosan kan bas\u0131nc\u0131n\u0131 d\u00fczenleyebilir ve hipertansiyonu \u00f6nleyebilir.
\nKitin, serum total kolesterol ve trigliseridlerini d\u00fczenleyebilir. Bunlar aras\u0131nda HDL, hipertansiyonun su\u00e7lusu olan klor\u00fcr iyonlar\u0131n\u0131 ba\u011flay\u0131p v\u00fccuttan uzakla\u015ft\u0131rabilir ve bu da hipertansiyonun neden oldu\u011fu \u00e7e\u015fitli hastal\u0131klar\u0131 \u00f6nleyebilir. Genellikle tuz yoluyla al\u0131n\u0131r. 2010 y\u0131l\u0131ndan bu yana bir\u00e7ok insan a\u015f\u0131r\u0131 tuz t\u00fcketmektedir. Kitosan, klor\u00fcr ve amonyak iyonlar\u0131 aras\u0131ndaki kendi adsorpsiyonu yoluyla klor\u00fcr iyonlar\u0131n\u0131 atar. Daha \u00f6nce de belirtildi\u011fi gibi, klor\u00fcr iyonlar\u0131 y\u00fcksek tansiyonun sorumlusudur. Kitosan, benzersiz pozitif y\u00fckl\u00fc \u00f6zelli\u011fi sayesinde negatif y\u00fckl\u00fc klor\u00fcr iyonlar\u0131n\u0131 ba\u011flayabilir ve salg\u0131layabilir, bu da kan bas\u0131nc\u0131nda d\u00fc\u015f\u00fc\u015fe neden olur. Uzun s\u00fcreli kitosan kullan\u0131m\u0131 kandaki asidik at\u0131klar\u0131 uzakla\u015ft\u0131rabilir, kan damarlar\u0131n\u0131 yumu\u015fatabilir, esnekli\u011fi art\u0131rabilir ve y\u00fcksek kan bas\u0131nc\u0131n\u0131 temelden d\u00fczenleyip hafifletebilir. Kitosan\u0131n benzersizli\u011fi, kan bas\u0131nc\u0131n\u0131 ve kan \u015fekerini iki y\u00f6nl\u00fc d\u00fczenlemesini de i\u00e7erir, yani d\u00fc\u015f\u00fck kan \u015fekeriniz ve d\u00fc\u015f\u00fck kan bas\u0131nc\u0131n\u0131z varsa, normal olman\u0131z i\u00e7in kan bas\u0131nc\u0131n\u0131z\u0131 ve kan \u015fekerinizi h\u0131zl\u0131 bir \u015fekilde d\u00fczenlemek i\u00e7in kendi g\u00fc\u00e7l\u00fc i\u015flevini etkinle\u015ftirecektir. Bu nedenle kitosan, \u00f6zellikle \u00e7ok fazla tuz t\u00fcketenlerde hipertansiyonu \u00f6nlemeye yard\u0131mc\u0131 olur!<\/p>\n

Be\u015finci olarak, kan ya\u011flar\u0131n\u0131 d\u00fczenler ve kardiyovask\u00fcler ve serebrovask\u00fcler hastal\u0131klar\u0131 \u00f6nler.
\nKitosan, lipitlerin sindirimini ve emilimini \u00f6nleyebilir, kolesterol\u00fc adsorbe edebilir ve v\u00fccuttan uzakla\u015ft\u0131rabilir, kolesterol\u00fcn d\u00f6n\u00fc\u015f\u00fcm\u00fcn\u00fc te\u015fvik edebilir, b\u00f6ylece kolesterol d\u00fc\u015f\u00fcr\u00fcl\u00fcr, b\u00f6ylece kardiyovask\u00fcler ve serebrovask\u00fcler hastal\u0131klar\u0131 \u00f6nler ve iyile\u015ftirir. Kitosan\u0131n kolesterol\u00fc d\u00fc\u015f\u00fcrmek i\u00e7in iki mekanizmas\u0131 vard\u0131r. \u0130lk olarak kitosan, ya\u011f emilimini kolayla\u015ft\u0131ran enzim olan lipaz\u0131n aktivitesini inhibe eder. Lipaz v\u00fccut taraf\u0131ndan emilmek \u00fczere ya\u011flar\u0131 par\u00e7alar. Di\u011feri ise safra asitlerinin at\u0131l\u0131m\u0131d\u0131r. Safra asitleri at\u0131ld\u0131ktan sonra, kandaki kolesterol safra asitleri yapmak i\u00e7in kullan\u0131l\u0131r. Bu iki mekanizma kitosan\u0131 g\u00fc\u00e7l\u00fc bir kolesterol tutucu yapar. Ve hi\u00e7bir yan etkisi yoktur.<\/p>\n

Alt\u0131nc\u0131 olarak, kitosan \"insan v\u00fccudunun \u00e7evre koruma maddesi\" olarak bilinir.
\nKitosan, LDL, kolesterol, gliserol ve di\u011fer at\u0131klar gibi y\u00fcks\u00fcz polar partik\u00fclleri polar adsorpsiyon \u015feklinde v\u00fccuttan uzakla\u015ft\u0131rabilmektedir. Elektrostatik adsorpsiyon \u015feklinde, ya\u011f asitleri, safra asitleri, laktik asit, klor\u00fcr iyonlar\u0131 vb. gibi negatif y\u00fckl\u00fc partik\u00fcller v\u00fccuttan at\u0131l\u0131r.<\/p>\n

Yedincisi: H\u00fccrelerin ya\u015flanma etkisini yava\u015flat\u0131r ve serbest radikallerin organizmaya verdi\u011fi zarar\u0131 engeller.
\nV\u00fccuttaki kitin, serbest radikalleri temizleme ve peroksidasyonu \u00f6nleme i\u015flevini yerine getirmeye devam edecek; organizman\u0131n doku h\u00fccrelerine verilen zarar\u0131 azaltacak ve h\u00fccrelerin ya\u015flanmas\u0131n\u0131 yava\u015flatmada \u015f\u00fcphesiz rol oynayacak olan h\u00fccrelerin i\u015flevine m\u00fcdahale edecektir. Serbest radikaller kimyasal olarak olduk\u00e7a aktiftir ve insan ya\u015fam aktivitelerindeki bir\u00e7ok biyokimyasal reaksiyonun ara metabolik \u00fcr\u00fcnleridir. Serbest radikallerin v\u00fccutta a\u015f\u0131r\u0131 birikmesini \u00f6nlemek i\u00e7in, insan v\u00fccudu bu serbest radikalleri ortadan kald\u0131rabilecek baz\u0131 maddeler \u00fcretmek zorundad\u0131r - serbest radikal eliminat\u00f6rleri. 35. PLA Hastanesi He Deqing ve di\u011fer kitosan amin serbest radikalleri temizleme ve peroksidasyon inhibisyonu hayvan testleri yapt\u0131, test sonu\u00e7lar\u0131na g\u00f6re, v\u00fccuttaki kitosan amin serbest radikalleri temizleme ve peroksidasyon inhibisyonu i\u015flevini oynamaya devam edecek.<\/p>\n

Sekizinci olarak, kitosan radyasyon hastal\u0131\u011f\u0131n\u0131 \u00f6nleyebilir ve v\u00fccuttaki a\u011f\u0131r metalleri ortadan kald\u0131rabilir.
\nKitosan, radyasyon hasar\u0131 taraf\u0131ndan \u00fcretilen \u00e7ok say\u0131da serbest radikali engelleyebilir, ba\u011f\u0131\u015f\u0131kl\u0131k fonksiyonunu art\u0131rabilir, enfeksiyonu \u00f6nleyebilir, radyoterapi ve kemoterapide kanser hastalar\u0131n\u0131n toksik yan etkilerini azaltabilir ve \u0131\u015f\u0131nlara maruz kalmaktan kaynaklanan mesleki hastal\u0131klar\u0131 \u00f6nleyebilir. Kitosan\u0131n dikkat \u00e7ekici \u00f6zelliklerinden biri de adsorpsiyon kapasitesidir. Metal iyonlar\u0131, kolesterol, trigliseritler, safra asitleri ve organik c\u0131va gibi bir\u00e7ok d\u00fc\u015f\u00fck molek\u00fcl a\u011f\u0131rl\u0131kl\u0131 malzeme kitosan taraf\u0131ndan adsorbe edilebilir. \u00d6zellikle, kitosan sadece magnezyum ve potasyumu de\u011fil, ayn\u0131 zamanda \u00e7inko, kalsiyum, c\u0131va ve uranyumu da adsorbe edebilir. Kitosan\u0131n adsorpsiyon aktivitesi se\u00e7ici olabilir. Bu metal iyonlar\u0131n\u0131n v\u00fccutta \u00e7ok y\u00fcksek konsantrasyonda bulunmas\u0131 zararl\u0131d\u0131r. \u00d6rne\u011fin, kandaki y\u00fcksek bak\u0131r iyonu konsantrasyonu bak\u0131r toksisitesine ve hatta kanserojen sonu\u00e7lara yol a\u00e7abilir. Kitin bir t\u00fcr polimer malzemedir, polimer malzemenin \u00e7\u00f6zeltisi belirli bir konsantrasyonda viskoziteye sahiptir ve ayn\u0131 zamanda \u00f6zel molek\u00fcler yap\u0131 bile\u015fimi nedeniyle y\u00fczey emme kabiliyetini de daha g\u00fc\u00e7l\u00fc hale getirebilir, dahas\u0131, kitinin molek\u00fcler yap\u0131s\u0131nda \u00e7ok say\u0131da polar grup vard\u0131r, bu da bir\u00e7ok y\u00fcks\u00fcz polar partik\u00fcl\u00fc adsorbe edebilir ve bunlar\u0131 v\u00fccuttan d\u0131\u015far\u0131 atabilir.<\/p>\n

Dokuzuncu olarak, kitinin bakterisidal ve antibakteriyel etkileri vard\u0131r.
\nKitinin patojenik organizmalar \u00fczerindeki inhibit\u00f6r etkisi uzun s\u00fcredir ara\u015ft\u0131r\u0131lmaktad\u0131r. Toz kitosan, kitin veya yenge\u00e7 kabuklar\u0131 ile muamele edilen agar plakalar\u0131 \u00fczerinde k\u00fclt\u00fcrlenen insan epidermal bakterileri \u00f6ld\u00fcr\u00fclm\u00fc\u015ft\u00fcr. Zhejiang \u00dcniversitesi, Biyokimyasal Ara\u015ft\u0131rma Enstit\u00fcs\u00fc'nden Zheng Lianying ve arkada\u015flar\u0131, kitosan aminin antibakteriyel mekanizmas\u0131n\u0131 \u00f6nermi\u015ftir: kitosan amin, infiltrasyon yoluyla h\u00fccre g\u00f6vdesine girer, h\u00fccre g\u00f6vdesindeki anyonlarla sitoplazmay\u0131 emer ve flok\u00fclasyon meydana gelir, h\u00fccrelerin normal fizyolojik aktivitelerini bozar, b\u00f6ylece bakterileri \u00f6ld\u00fcr\u00fcr.<\/p>\n

Onuncu olarak, kitosan yara iyile\u015fmesini destekleme etkisine sahiptir.
\nKitin, yara gran\u00fclasyon dokusu b\u00fcy\u00fcmesini belirgin bir \u015fekilde te\u015fvik eder, iyile\u015fme h\u0131z\u0131n\u0131 art\u0131r\u0131r, \u00e7e\u015fitli bakterileri inhibe eder ve \u00f6ld\u00fcr\u00fcr, endotelyal b\u00fcy\u00fcmeyi te\u015fvik eder, fibr\u00f6z doku proliferasyonunu ve skar olu\u015fumunun rol\u00fcn\u00fc azalt\u0131r. Travma, yan\u0131k, yatak yaralar\u0131 vb. tedavisi gibi cerrahi alan\u0131nda kitin geni\u015f bir kullan\u0131m de\u011ferine sahiptir.<\/p>\n

On birincisi, kitinin kozmetik bir etkisi vard\u0131r.
\nKitin do\u011fal bir polimer bile\u015fi\u011fidir, iyi nem tutma, adsorpsiyon, viskozite, antibakteriyel, antistatik, film olu\u015fturma, tarama, yumu\u015fakl\u0131k ve aktivasyon, h\u00fccrelerin onar\u0131m\u0131 \u00f6zelliklerine sahiptir.<\/p>\n

On ikincisi, kitin karaci\u011fer hastal\u0131klar\u0131n\u0131n \u00f6nlenmesi ve tedavisi i\u00e7in yeni bir umuttur.
\nKitin, v\u00fccut ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131n\u0131 geli\u015ftirme, detoksifikasyon ve detoksifikasyon ve h\u00fccreleri aktive etme i\u015flevlerine sahiptir. Kitin sadece hepatit ve ya\u011fl\u0131 karaci\u011fer olu\u015fumunu \u00f6nlemek i\u00e7in karaci\u011ferdeki biyolojik enzimleri aktive etmekle kalmaz, ayn\u0131 zamanda ba\u011f\u0131\u015f\u0131kl\u0131k sistemini g\u00fc\u00e7lendirme, kolesterol ve n\u00f6tr ya\u011f emilimini \u00f6nleme i\u015flevine sahiptir ve h\u00fccre dirili\u015finde g\u00fc\u00e7l\u00fc bir rol oynayabilir.<\/p>\n

On \u00fc\u00e7\u00fcnc\u00fcs\u00fc, v\u00fccudun asidik ortam\u0131n\u0131 iyile\u015ftirmek i\u00e7in.
\nKitinin alkali grubu sayesinde, sa\u011fl\u0131\u011fa elveri\u015fli olmayan asidik v\u00fccut s\u0131v\u0131lar\u0131, sa\u011fl\u0131\u011fa elveri\u015fli olan zay\u0131f alkali seviyeye geri y\u00fcklenir ve d\u00fczenlenir, asidik v\u00fccudu iyile\u015ftirir, hastal\u0131\u011fa kolay de\u011fildir. Bu nedenle, sa\u011fl\u0131kl\u0131 insanlar ve sa\u011fl\u0131ks\u0131z durumdaki insanlar d\u00fczenli olarak kitosan t\u00fcketse bile, sa\u011fl\u0131k a\u00e7\u0131s\u0131ndan da bir rol oynayacakt\u0131r. \u0130nsan v\u00fccudundaki kan veya di\u011fer v\u00fccut s\u0131v\u0131lar\u0131 belirli bir PH de\u011ferini korur. Genel olarak konu\u015fursak, v\u00fccut s\u0131v\u0131lar\u0131 zay\u0131f alkali olmal\u0131d\u0131r, aksi takdirde hastal\u0131klara yatk\u0131n olurlar. Bu nedenle, zay\u0131f alkali bir v\u00fccut s\u0131v\u0131s\u0131 ortam\u0131n\u0131n korunmas\u0131 insan sa\u011fl\u0131\u011f\u0131n\u0131n korunmas\u0131 i\u00e7in gereklidir. Kitosan ald\u0131ktan sonra, kitosan\u0131n alkalin geni sayesinde, sa\u011fl\u0131\u011fa elveri\u015fli olmayan asidik v\u00fccut s\u0131v\u0131s\u0131, sa\u011fl\u0131\u011fa elveri\u015fli olan zay\u0131f alkali seviyeye geri getirilebilir ve d\u00fczenlenebilir ve s\u00f6zde asidik v\u00fccut s\u0131v\u0131s\u0131 iyile\u015ftirilebilir ve insanlar hastal\u0131klara e\u011filimli olmayacakt\u0131r.<\/p>\n

On d\u00f6rd\u00fcnc\u00fc olarak, kemik ve eklem hastal\u0131klar\u0131n\u0131n tedavisi.
\nOrtopedik tedavide kitin, do\u011fru ve g\u00fcvenilir etkinli\u011fi ilk artrit olmal\u0131d\u0131r. Kitin t\u00fcrevleri kondrosit proteoglikan sentezini te\u015fvik edebilir, sinovyal s\u0131v\u0131 viskozitesini art\u0131rabilir, eklem k\u0131k\u0131rda\u011f\u0131 metabolizmas\u0131n\u0131 iyile\u015ftirebilir, osteoblastlar\u0131 osteoklastlar\u0131 ve fibroblastlar\u0131 kabuk olu\u015fumunu, aminosugar ve kondroitin s\u00fclfat\u0131 insan v\u00fccuduna h\u0131zland\u0131rabilir, bir yandan proteoglikanlar\u0131n, kolajen liflerin ve hyaluronik asit \u00fcretimini te\u015fvik etmek i\u00e7in, eklem k\u0131k\u0131rda\u011f\u0131n\u0131n \u00fcretimi i\u00e7in gereklidir. \u00d6te yandan, eklem k\u0131k\u0131rda\u011f\u0131n\u0131n y\u00fczeyini s\u00fcrekli olarak ya\u011flamak, s\u00fcrt\u00fcnmeyi azaltmak, b\u00f6ylece eklemlerin serbest\u00e7e ve esnek bir \u015fekilde hareket edebilmesi i\u00e7in sinovyal s\u0131v\u0131n\u0131n \u00fcretimini te\u015fvik etmek i\u00e7in sinovyal membran\u0131n etkisi yoluyla. Ayn\u0131 zamanda, eklem besinlerinin ta\u015f\u0131y\u0131c\u0131s\u0131 olarak sinovyal s\u0131v\u0131, osteoartropatinin iyile\u015fmesine ve kemik k\u0131r\u0131\u011f\u0131n\u0131n iyile\u015fmesine yard\u0131mc\u0131 olan eklem k\u0131k\u0131rda\u011f\u0131 i\u00e7in yeterli beslenme sa\u011flayabilir.<\/p>\n

On be\u015fincisi, kitin gastrointestinal fonksiyonu iyile\u015ftirebilir.
\nMide suyunda \u00e7\u00f6z\u00fcnen kitin, gastrointestinal duvarda ayr\u0131lmas\u0131 kolay olmayan koruyucu bir tabaka olu\u015fturmak i\u00e7in bir jel haline gelir, stim\u00fclasyonun hasarl\u0131 y\u00fczeyinde mide asidinin inhibisyonu, korozyon ve \u00fclserlerin onar\u0131m\u0131 ve iyile\u015fmesini te\u015fvik eder.<\/p>\n

On alt\u0131nc\u0131s\u0131, kitin ba\u011f\u0131rsak bifidobakterilerinin b\u00fcy\u00fcmesini te\u015fvik edebilir.
\nBifidobakteriler \u00fczerindeki kitin, rol\u00fcn b\u00fcy\u00fcmesini te\u015fvik etmeli, ba\u011f\u0131rsak disfonksiyonunu \u00f6nlemek ve ba\u011f\u0131rsak enfeksiyonlar\u0131n\u0131 \u00f6nlemek i\u00e7in ba\u011f\u0131rsak patojenik bakterilerinin ve bozulma bakterilerinin b\u00fcy\u00fcmesini engelleyebilir, besinlerin emilimini art\u0131rabilir. Kitin, ba\u011f\u0131rsaklarda k\u00fc\u00e7\u00fck molek\u00fcler a\u011f\u0131rl\u0131kl\u0131 chito-oligosakkaritlere ayr\u0131\u015ft\u0131r\u0131labilir ve bu t\u00fcr oligosakkaritlerin ba\u011f\u0131rsaklardaki yararl\u0131 bakteriler i\u00e7in besin kayna\u011f\u0131 oldu\u011fu kan\u0131tlanm\u0131\u015ft\u0131r, bu da ba\u011f\u0131rsaklardaki yararl\u0131 bakterilerin b\u00fcy\u00fcmesini ve \u00e7o\u011falmas\u0131n\u0131 te\u015fvik edebilir. Bu, uzun s\u00fcreli antibiyotik kullan\u0131m\u0131n\u0131n neden oldu\u011fu haz\u0131ms\u0131zl\u0131k gibi disbiyozla sonu\u00e7lanan gastrointestinal hastal\u0131klar \u00fczerinde iyi bir etkidir. Bebekler ve k\u00fc\u00e7\u00fck \u00e7ocuklar, kitosan alarak d\u00fczeltilmesi gereken s\u00fct haz\u0131ms\u0131zl\u0131\u011f\u0131na e\u011filimlidir.<\/p>\n

On yedincisi, sinir ve endokrin sisteminin kitinle d\u00fczenlenmesi.
\nEnzimlerin etkisi alt\u0131nda oligoglukozamin ve glukozamine d\u00f6n\u00fc\u015fen \"kitin\" fizyolojik aktivitesi \u00f6nemli \u00f6l\u00e7\u00fcde artm\u0131\u015f, vagus sinirini ve parasempatik sinirleri uyararak ince arterlerin ilgili dokular\u0131n\u0131n uyar\u0131labilirli\u011fini ve mikro arteriyollerin geni\u015flemesini, kan h\u0131z\u0131n\u0131, kan ak\u0131\u015f\u0131n\u0131 art\u0131rarak mikrosirk\u00fclasyonu iyile\u015ftirmi\u015f, spesifik fonksiyonlar g\u00fc\u00e7lendirilmi\u015ftir. Endokrin organlardaki sekretin seviyesi y\u00fckselir ve bez h\u00fccrelerinin salg\u0131lama i\u015flevi artar. \u00c7e\u015fitli fizyolojik aktif maddeler buna g\u00f6re iyi bir d\u00fczenleme \u00fcretir.<\/p>\n

On sekizincisi, kitin \"hemostaz ve p\u0131ht\u0131la\u015fma.
\n\"Kitin \"in kanamay\u0131 durdurabildi\u011fi klinik t\u0131p taraf\u0131ndan onaylanm\u0131\u015ft\u0131r. Mekanizma, kitinin p\u0131ht\u0131la\u015fma s\u00fcrecindeki baz\u0131 ba\u011flant\u0131lar\u0131 aktive edebilmesidir. Kitinin pozitif y\u00fckl\u00fc amino grubu, p\u0131ht\u0131la\u015fma s\u00fcrecini te\u015fvik etmek i\u00e7in sinir h\u00fccreleri \u00fczerindeki negatif y\u00fckl\u00fc amino asit kal\u0131nt\u0131s\u0131 resept\u00f6rleri ile etkile\u015fime girer. Etkilenen b\u00f6lgede \"kitin\" ile trombosit p\u0131ht\u0131la\u015fmas\u0131, p\u0131ht\u0131la\u015fma s\u00fcrecini h\u0131zland\u0131rmak i\u00e7in trombositleri uyar\u0131r.<\/p>","protected":false},"excerpt":{"rendered":"

Kitin, kitosan ve kitooligosakkaritlerin hepsi kabuklular\u0131n (\u00f6rne\u011fin karidesler, yenge\u00e7ler, kabuklu deniz hayvanlar\u0131) kabuklar\u0131ndan elde edilen polisakkaritlerdir ve yap\u0131 ve kullan\u0131m a\u00e7\u0131s\u0131ndan baz\u0131 farkl\u0131l\u0131klar\u0131 vard\u0131r: 1. Kitin (Kitosan): Kitin, \u03b2-1,4-glikozidik ba\u011flarla ba\u011flanm\u0131\u015f N-asetilglukozamin monomerlerinden olu\u015fan do\u011frusal bir polisakkarittir. Kabuklular\u0131n d\u0131\u015f iskeletinin \u00f6nemli bir bile\u015fenidir ve ayn\u0131 zamanda [...]<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[105],"tags":[],"class_list":["post-6882","post","type-post","status-publish","format-standard","hentry","category-medicine-news"],"yoast_head":"\nWhat is the difference between chitin, chitosan and chitosan? - Longchang Chemical<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangchemical.com\/tr\/what-is-the-difference-between-chitin-chitosan-and-chitosan\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"What is the difference between chitin, chitosan and chitosan? - Longchang Chemical\" \/>\n<meta property=\"og:description\" content=\"Chitin, chitosan and chitooligosaccharides are all polysaccharides extracted from the shells of crustaceans (e.g. shrimps, crabs, shellfish), and they have some differences in structure and use: 1. 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