{"id":4514,"date":"2021-04-22T07:03:58","date_gmt":"2021-04-22T07:03:58","guid":{"rendered":"https:\/\/longchangchemical.com\/?p=4514"},"modified":"2024-09-28T11:56:15","modified_gmt":"2024-09-28T11:56:15","slug":"overview-of-the-methods","status":"publish","type":"post","link":"https:\/\/longchangchemical.com\/tr\/overview-of-the-methods\/","title":{"rendered":"Enzimleri Manyetik Biyopolimer Mikrok\u00fcreler \u00dczerine \u0130mmobilize Etme Y\u00f6ntemlerine Genel Bak\u0131\u015f"},"content":{"rendered":"

Manyetik biyopolimer mikrok\u00fcreler, manyetik olarak duyarl\u0131 ve biyolojik olarak aktif mikrok\u00fcreler olu\u015fturmak i\u00e7in biyolojik malzemeleri ve inorganik manyetik malzemeleri birle\u015ftiren yeni bir kompozit malzemedir. \u00d6zellikleri inorganik manyetik malzemelere, biyolojik malzemelere ve bunlar\u0131n etkile\u015fim y\u00f6ntemine ba\u011fl\u0131d\u0131r. \u015eu anda en yayg\u0131n olarak kullan\u0131lan ve \u00fczerinde \u00e7al\u0131\u015f\u0131lan manyetik malzeme Fe3<\/sub>O4<\/sub>\u00a0manyetik nanopartik\u00fcller. Geni\u015f spesifik y\u00fczey alan\u0131, iyi biyouyumlulu\u011fu ve y\u00fcksek manyetik tepkisi nedeniyle, h\u0131zl\u0131 ay\u0131rma ve hedefli hareket sa\u011flayabilir, bu nedenle g\u0131da ve t\u0131bbi bak\u0131m, \u00e7evre koruma ve di\u011fer alanlarda yayg\u0131n olarak kullan\u0131labilir. Biyopolimer malzemeler temel olarak kitosan, sodyum aljinat, jelatin vb. i\u00e7erir. Bunlar aras\u0131nda kitosan, iyi biyouyumluluk, yenilenebilir kaynaklar ve biyolojik olarak par\u00e7alanabilirlik \u00f6zellikleri nedeniyle en \u00e7ok \u00e7al\u0131\u015f\u0131lan biyolojik malzemedir. Kitosan ve manyetik malzemeden olu\u015fan yeni bir kompozit malzeme t\u00fcr\u00fc, her iki m\u00fckemmel \u00f6zelli\u011fe de sahiptir, bu nedenle \u00e7e\u015fitli alanlarda geni\u015f uygulama olanaklar\u0131na sahiptir.<\/h4>\r\n\r\n\r\n\r\n
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1. Manyetik biyopolimer mikrok\u00fcrelerin yap\u0131s\u0131 ve \u00f6zellikleri<\/strong><\/h2>\r\n\r\n\r\n\r\n
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Manyetik biyopolimer mikrok\u00fcrelerin yap\u0131s\u0131 \u00fc\u00e7 tip i\u00e7erir: (1) \u00e7ekirdek-kabuk yap\u0131s\u0131; (2) hibrit yap\u0131; (3) \u015eekil 1'de g\u00f6sterildi\u011fi gibi \u00e7ok katmanl\u0131 sandvi\u00e7 yap\u0131.<\/h4>\r\n\r\n\r\n\r\n
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\u015eekil 1 Manyetik biyopolimer mikrok\u00fcrelerin yap\u0131s\u0131<\/h4>\r\n\r\n\r\n\r\n
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Manyetik biyopolimer mikrok\u00fcreler, onlar\u0131 enzim immobilizasyonu i\u00e7in daha uygun hale getiren bir\u00e7ok ola\u011fan\u00fcst\u00fc \u00f6zelli\u011fe sahiptir. \u00d6rne\u011fin (1) y\u00fczey alan\u0131 etkisi. Genel olarak, manyetik biyopolimer mikrok\u00fcrelerin partik\u00fcl boyutu mikron hatta nanometre seviyesine ula\u015ft\u0131\u011f\u0131nda, spesifik y\u00fczey alan\u0131 artt\u0131k\u00e7a, mikrok\u00fcrelerin grup yo\u011funlu\u011fu ve se\u00e7ici adsorpsiyon performans\u0131 da artar ve mikrok\u00fcrelerin stabilitesi \u00f6nemli \u00f6l\u00e7\u00fcde artar. (2) Manyetik etki. Fe'nin \u00e7ap\u0131 artt\u0131\u011f\u0131nda3<\/sub>O4<\/sub>\u00a0kristal 30 nm'den k\u00fc\u00e7\u00fckt\u00fcr, s\u00fcper para-manyetizmaya sahiptir, yani d\u0131\u015f manyetik alan ko\u015fulu alt\u0131nda manyetizma \u00e7ok b\u00fcy\u00fckt\u00fcr. Harici manyetik alan kald\u0131r\u0131ld\u0131\u011f\u0131nda, manyetizmas\u0131 h\u0131zla kaybolur, b\u00f6ylece mikrok\u00fcre harici manyetik alan ko\u015fulu alt\u0131nda manyetik y\u00f6nelime sahip olur ve manyetik olmayan malzemelerden h\u0131zla ayr\u0131l\u0131r ve manyetik bir alanda kal\u0131c\u0131 olarak m\u0131knat\u0131slanmaz, bu nedenle sonraki kullan\u0131m\u0131 etkilemez. (3) Biyouyumluluk. Do\u011fada, proteinler ve polisakkaritler gibi biyolojik malzemeler biyouyumlulu\u011fa sahiptir, bu da biyomedikal m\u00fchendisli\u011finde \u00f6nemli uygulamalara sahip olmalar\u0131n\u0131 sa\u011flar. (4) Fonksiyonel temel \u00f6zellikler. Kitosan ve sodyum aljinat gibi biyolojik malzemeler, biyolojik olarak aktif maddelerle kovalent olarak birle\u015ftirilebilen veya belirli kimyasal gruplarla modifiye edilebilen bol miktarda aktif gruba (-OH, -COOH, -NH2) sahiptir.<\/h4>\r\n\r\n\r\n\r\n
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2. Manyetik biyopolimer mikrok\u00fcrelerin haz\u0131rlanmas\u0131<\/strong><\/h2>\r\n\r\n\r\n\r\n
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Manyetik biyopolimer mikrok\u00fcrelerin haz\u0131rlanmas\u0131 iki ad\u0131ma ayr\u0131l\u0131r. \u0130lk ad\u0131m manyetik nanopartik\u00fcllerin haz\u0131rlanmas\u0131d\u0131r. \u015eu anda Fe haz\u0131rlamak i\u00e7in kullan\u0131lan y\u00f6ntemler3<\/sub>O4<\/sub>\u00a0manyetik nanopartik\u00fcller temel olarak kimyasal birlikte \u00e7\u00f6keltme, demir tuzu termal ayr\u0131\u015ft\u0131rma, mikroem\u00fclsiyon ve hidrotermal y\u00f6ntemleri i\u00e7erir. Bunlar aras\u0131nda, kimyasal birlikte \u00e7\u00f6keltme y\u00f6ntemi basit ve kullan\u0131m\u0131 kolayd\u0131r ve en yayg\u0131n kullan\u0131lan haz\u0131rlama y\u00f6ntemidir. Fe sentezlemek i\u00e7in kimyasal birlikte \u00e7\u00f6keltme y\u00f6nteminin prensibi3<\/sub>O4<\/sub>\u00a0demir oksit sentezlemek i\u00e7in belirli bir oranda Fe-kar\u0131\u015f\u0131m\u0131 i\u00e7eren kar\u0131\u015f\u0131k bir tuz \u00e7\u00f6zeltisini \u0131s\u0131tmak ve kar\u0131\u015ft\u0131rmakt\u0131r.2+<\/sup>\u00a0ve Fe3+<\/sup>\u00a0(1:2) anaerobik ko\u015fullar alt\u0131nda ve h\u0131zl\u0131 bir \u015fekilde k\u00fcl suyu (amonyak veya NaOH) ekleyerek. Xu ve arkada\u015flar\u0131 kimyasal birlikte \u00e7\u00f6keltme y\u00f6ntemini kullanarak 4,34 mmol FeCl2\u9458<\/sub>4H2O ve 8,67 mmol FeCl3<\/sub>-6H2<\/sub>O ekleyin ve sistemi azot alt\u0131nda 85 \u2103'ye \u0131s\u0131t\u0131n. Tamamen \u00e7\u00f6z\u00fcnd\u00fckten sonra, h\u0131zl\u0131 bir \u015fekilde 25 mL konsantre amonyak ekleyin ve belirli miktarda sodyum sitrat ekleyin, ard\u0131ndan Fe3<\/sub>O4<\/sub>\u00a0manyetik nanopartik\u00fcller iyi mono da\u011f\u0131l\u0131m ve manyetik duyarl\u0131l\u0131k ile sentezlenmi\u015ftir.<\/h4>\r\n\r\n\r\n\r\n
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Manyetik nanopartik\u00fcllerin haz\u0131rlanmas\u0131ndan sonra, manyetik kitosan mikrok\u00fcreleri haz\u0131rlamak i\u00e7in kitosan ile \u00e7apraz ba\u011flanmas\u0131 gerekir. \u015eu anda, manyetik kitosan mikrok\u00fcrelerin sentez y\u00f6ntemleri temel olarak em\u00fclsiyon \u00e7apraz ba\u011flama y\u00f6ntemi, sprey kurutma y\u00f6ntemi, fotokimyasal y\u00f6ntem ve in-situ y\u00f6ntemi i\u00e7erir. Bunlar aras\u0131nda em\u00fclsiyon \u00e7apraz ba\u011flama y\u00f6ntemi daha basittir ve en yayg\u0131n kullan\u0131lan\u0131d\u0131r. Em\u00fclsiyon \u00e7apraz ba\u011flama y\u00f6ntemi, Fe3<\/sub>O4<\/sub>\u00a0veya manyetik s\u0131v\u0131y\u0131 ya\u011f i\u00e7inde su mikroem\u00fclsiyon sistemi olu\u015fturmak i\u00e7in kitosan, y\u00fczey aktif madde ve ya\u011f faz\u0131 i\u00e7eren kar\u0131\u015f\u0131k bir s\u0131v\u0131ya ekleyin ve ard\u0131ndan glutaraldehit ekleyin, sistemde glutaraldehit ve kitosan bir Schiff baz\u0131 olu\u015fturmak i\u00e7in \u00e7apraz ba\u011flanma reaksiyonu ger\u00e7ekle\u015ftirecek ve kitosan bir a\u011fa \u00e7apraz ba\u011flanacak ve ard\u0131ndan Fe3<\/sub>O4<\/sub>\u00a0(\u015eekil 2'de g\u00f6sterildi\u011fi gibi). Jiang ve arkada\u015flar\u0131, d\u00fczenli k\u00fcresel \u015fekillere ve p\u00fcr\u00fczs\u00fcz y\u00fczeylere sahip manyetik kitosan mikrok\u00fcreleri sentezlemek i\u00e7in s\u0131ras\u0131yla y\u00fczey aktif madde, da\u011f\u0131t\u0131c\u0131 ve \u00e7apraz ba\u011flama maddesi olarak Span 80, s\u0131v\u0131 parafin ve glutaraldehit kullanarak em\u00fclsiyon \u00e7apraz ba\u011flama y\u00f6ntemini kullanm\u0131\u015flard\u0131r.<\/h4>\r\n\r\n\r\n\r\n
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\u015eekil 2 Em\u00fclsiyon \u00e7apraz ba\u011flama y\u00f6ntemiyle manyetik kitosan mikrok\u00fcrelerin sentezinin \u015fematik diyagram\u0131<\/h4>\r\n\r\n\r\n\r\n
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3. Manyetik kompozit mikrok\u00fcreler \u00fczerine immobilize edilmi\u015f enzim<\/strong><\/h2>\r\n\r\n\r\n\r\n
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Manyetik kitosan mikrok\u00fcreler ba\u015far\u0131yla haz\u0131rland\u0131ktan sonra, enzim kullan\u0131m i\u00e7in mikrok\u00fcreler \u00fczerine immobilize edilebilir. Kitosan aktif amino gruplar\u0131 ve hidroksil gruplar\u0131 bak\u0131m\u0131ndan zengin oldu\u011fundan, karboksil gruplar\u0131, amino gruplar\u0131, epoksi gruplar\u0131, iki i\u015flevli gruplar vb. ile reaksiyona girebilir. Manyetik kitosan mikrok\u00fcreler, farkl\u0131 immobilizasyon ihtiya\u00e7lar\u0131n\u0131 kar\u015f\u0131lamak i\u00e7in grup modifiye edilmi\u015ftir. Spesifik immobilize enzimlerin haz\u0131rlama y\u00f6ntemleri a\u015fa\u011f\u0131da fonksiyonel gruplara g\u00f6re tan\u0131t\u0131lm\u0131\u015ft\u0131r.<\/h4>\r\n\r\n\r\n\r\n
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1) Karboksil modifiye manyetik kompozit mikrok\u00fcreler \u00fczerine immobilize edilmi\u015f enzim<\/h3>\r\n\r\n\r\n\r\n

Karboksil modifiye manyetik kompozit mikrok\u00fcreler, sulu bir \u00e7\u00f6zelti i\u00e7inde karbodiimid ba\u011flanmas\u0131yla aktive edildikten sonra enzimin amino grubuna kovalent olarak ba\u011flanabilir ve b\u00f6ylece enzim molek\u00fcl\u00fc manyetik kompozit mikrok\u00fcreler \u00fczerinde immobilize edilebilir (\u015eekil 3). Zhu Yihua ve di\u011ferleri, stirenle muamele edilmi\u015f manyetik s\u0131v\u0131y\u0131 ve monomer metil akrilat\u0131 \u00e7apraz ba\u011flay\u0131c\u0131 monomer divinilbenzen arac\u0131l\u0131\u011f\u0131yla kopolimerize etmek i\u00e7in geli\u015ftirilmi\u015f bir s\u00fcspansiyon polimerizasyon y\u00f6ntemi kullanm\u0131\u015f ve ard\u0131ndan iyi mono da\u011f\u0131l\u0131m ve zengin karboksil gruplar\u0131na sahip bir manyetik kompozit elde etmek i\u00e7in alkali hidroliz kullanm\u0131\u015ft\u0131r. Mikrok\u00fcreler, karbodiimid ba\u011flama ile aktive edildikten sonra laktaz\u0131 immobilize etmek i\u00e7in kullan\u0131l\u0131r. En y\u00fcksek aktivite yakla\u015f\u0131k 360 U-g-1<\/sup>ve enzimin \u00e7apraz ba\u011flama etkinli\u011fi yakla\u015f\u0131k 20%'dir.<\/h4>\r\n\r\n\r\n\r\n
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\u015eekil 3 Karboksil modifiye manyetik kompozit mikrok\u00fcreler \u00fczerine immobilize enzim haz\u0131rlanmas\u0131n\u0131n \u015fematik diyagram\u0131<\/h4>\r\n\r\n\r\n\r\n
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2) Amino modifiye manyetik kompozit mikrok\u00fcreler immobilize enzim<\/h3>\r\n\r\n\r\n\r\n

Amino modifiye manyetik kompozit mikrok\u00fcreler uygun miktarda glutaraldehit ile birle\u015ftirilip aktive edildikten sonra, enzim \u00fczerindeki amino grubuna kovalent olarak ba\u011flanabilir ve b\u00f6ylece enzim molek\u00fcllerini manyetik mikrok\u00fcreler \u00fczerinde immobilize edebilir (\u015eekil 4). Liu Yu ve arkada\u015flar\u0131 art arda monodispers manyetik SiO2<\/sub>\u00a0partik\u00fclleri kimyasal birlikte \u00e7\u00f6keltme y\u00f6ntemi ve sol-jel y\u00f6ntemiyle par\u00e7alam\u0131\u015f, silan ba\u011flama maddesi ile amino gruplar\u0131yla modifiye etmi\u015f ve \u00e7apraz ba\u011flama maddesi olarak glutaraldehit ile lakkaz\u0131 immobilize etmi\u015ftir. Sonu\u00e7lar, immobilize lakkaz\u0131n 4 saat boyunca 60 \u2103 sabit s\u0131cakl\u0131kta tutuldu\u011funu ve hala 60.9% enzim aktivitesine sahip oldu\u011funu ve 10 kullan\u0131m d\u00f6ng\u00fcs\u00fcnden sonra hala 55%'den fazla enzim aktivitesine sahip oldu\u011funu ve termal stabilitesinin ve operasyonel stabilitesinin belirgin bir \u015fekilde artt\u0131\u011f\u0131n\u0131 g\u00f6stermi\u015ftir.<\/p>\r\n\r\n\r\n\r\n

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\u015eekil 4 Amino-modifiye manyetik kompozit mikrok\u00fcreler \u00fczerine immobilize enzim haz\u0131rlanmas\u0131n\u0131n \u015fematik diyagram\u0131<\/p>\r\n\r\n\r\n\r\n

3) Epoksi modifiye manyetik kompozit mikrok\u00fcreler immobilize enzim<\/h3>\r\n\r\n\r\n\r\n

Epoksi grubu son derece aktif bir gruptur. Modifikasyon olmaks\u0131z\u0131n biyolojik gruplara do\u011frudan kovalent olarak ba\u011flanabilir. Bu nedenle, epoksi modifiye manyetik kompozit mikrok\u00fcreler enzimi ba\u011flamak i\u00e7in enzim \u00fczerindeki amino grubuna kovalent olarak ba\u011fland\u0131ktan sonra, molek\u00fcller manyetik mikrok\u00fcreler \u00fczerinde immobilize edilir (\u015eekil 5). Yong ve arkada\u015flar\u0131 s\u00fcspansiyon polimerizasyonu ile oleik asit kapl\u0131 manyetik mikrok\u00fcreler haz\u0131rlam\u0131\u015ft\u0131r. Metanol ile aktivasyon sonras\u0131nda elde edilen hidrofilik epoksi bazl\u0131 manyetik mikrok\u00fcreler lipaz\u0131n immobilizasyonu i\u00e7in kullan\u0131lm\u0131\u015ft\u0131r. \u0130mmobilize enzim aktivitesinin tutma oran\u0131 64.2%'dir ve stabilitesi \u00f6nemli \u00f6l\u00e7\u00fcde artm\u0131\u015ft\u0131r.<\/h4>\r\n\r\n\r\n\r\n
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\u015eekil 5 Epoksi bazl\u0131 manyetik kompozit mikrok\u00fcreler \u00fczerine immobilize enzim haz\u0131rlanmas\u0131n\u0131n \u015fematik diyagram\u0131<\/p>\r\n\r\n\r\n\r\n

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4) \u0130ki fonksiyonlu gruplarla modifiye edilmi\u015f manyetik kompozit mikrok\u00fcreler \u00fczerine immobilize edilmi\u015f enzimler<\/h3>\r\n\r\n\r\n\r\n
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\u0130ki fonksiyonlu manyetik mikrok\u00fcrelerde, \u00f6ncelikle enzim molek\u00fcl\u00fcn\u00fcn karboksil gruplar\u0131 ve mikrok\u00fcreler \u00fczerindeki amino gruplar\u0131 iyon etkile\u015fimi ile ta\u015f\u0131y\u0131c\u0131 \u00fczerinde h\u0131zl\u0131 bir \u015fekilde immobilize edilir ve iyon etkile\u015fimi ile immobilize edilen enzim, s\u00fclfhidril ve amino gruplar\u0131 arac\u0131l\u0131\u011f\u0131yla ta\u015f\u0131y\u0131c\u0131 \u00fczerindeki epoksi gruplar\u0131 ile kovalent olarak etkile\u015fime girer. \u0130yonik etki ile h\u0131zl\u0131 sabitleme ve kovalent ba\u011f ile s\u0131k\u0131 sabitleme gibi ikili \u00f6zelliklere sahip olan enzimi daha da sabit hale getirin (\u015eekil 6'da g\u00f6sterildi\u011fi gibi). Li Xiutao ve arkada\u015flar\u0131, divinilbenzen \u00e7apraz ba\u011fl\u0131 poliakrilik asit mikrok\u00fcrelerin y\u00fczeyine \u00fc\u00e7 rastgele kopolimer f\u0131r\u00e7ay\u0131 Fe3<\/sub>O4<\/sub>\u00a0nanopartik\u00fcller i\u00e7inde da\u011f\u0131t\u0131lm\u0131\u015f ve daha sonra penisilin G a\u00e7ilaz\u0131 immobilize etmek i\u00e7in kullan\u0131lm\u0131\u015ft\u0131r. Sonu\u00e7lar, hem epoksi grubu hem de amino grubu ayn\u0131 anda eklenen immobilize enzimin aktivitesinin ve enzim aktivitesinin geri kazan\u0131m oran\u0131n\u0131n en y\u00fcksek oldu\u011funu, immobilizasyon kineti\u011finin sadece epoksi i\u00e7eren manyetik mikrok\u00fcrelerden daha iyi oldu\u011funu ve optimal pH de\u011ferinin ve s\u0131cakl\u0131k stabilitesinin Serbest enzimden daha y\u00fcksektir ve enzim aktivitesi, 10 kez tekrarlanan kullan\u0131mdan sonra 70%'yi korur.<\/h4>\r\n\r\n\r\n\r\n
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\u015eekil 6 \u0130ki fonksiyonlu gruplarla modifiye edilmi\u015f manyetik kompozit mikrok\u00fcreler \u00fczerine immobilize enzim haz\u0131rlanmas\u0131n\u0131n \u015fematik diyagram\u0131<\/h4>\r\n\r\n\r\n\r\n
\"\"<\/figure>\r\n\r\n\r\n\r\n

Son y\u0131llarda, bilim adamlar\u0131 naringinaz\u0131 immobilize etmek i\u00e7in kitosan, sodyum aljinat ve ipek proteini gibi do\u011fal biyopolimer malzemeler, epoksi re\u00e7ine ve polivinil alkol gibi organik bile\u015fikler, aktif karbon ve ene gibi grafit oksit karbon malzemeler gibi farkl\u0131 malzemeler kullanm\u0131\u015f ve baz\u0131 ara\u015ft\u0131rma sonu\u00e7lar\u0131 elde edilmi\u015f olsa da, ger\u00e7ek debittering uygulamalar\u0131nda, immobilize enzimlerin zay\u0131f asit direnci, meyve suyundan yava\u015f ayr\u0131lma veya eksik ayr\u0131lma gibi sorunlar vard\u0131r. Yukar\u0131daki sorunlarla ilgili olarak, bir sonraki makale bir ara\u015ft\u0131rma \u00e7al\u0131\u015fmas\u0131n\u0131 ayr\u0131nt\u0131l\u0131 olarak tan\u0131tacakt\u0131r. Bu \u00e7al\u0131\u015fmada, ara\u015ft\u0131rmac\u0131lar kitosan, manyetik Fe3<\/sub>O4<\/sub>\u00a0nanopartik\u00fcller ve silika kullan\u0131larak kompozit malzeme epoksi gruplar\u0131 ile modifiye edilmi\u015f ve daha sonra naringinaz \u00fczerine immobilize edilmi\u015ftir. Bu \u00e7al\u0131\u015fma, naringinaz immobilizasyon teknolojisi ara\u015ft\u0131rmalar\u0131n\u0131n daha ileri \u00e7al\u0131\u015fmalar\u0131 i\u00e7in veri temeli sa\u011flayacakt\u0131r.<\/h4>\r\n\r\n\r\n\r\n

\u015eimdi Bize Ula\u015f\u0131n!<\/b><\/strong><\/h2>\r\n

Fiyata ihtiyac\u0131n\u0131z varsa, l\u00fctfen a\u015fa\u011f\u0131daki forma ileti\u015fim bilgilerinizi doldurun, genellikle 24 saat i\u00e7inde sizinle ileti\u015fime ge\u00e7ece\u011fiz. Bana e-posta da g\u00f6nderebilirsiniz\u00a0info@longchangchemical.com<\/a><\/span>\u00a0\u00c7al\u0131\u015fma saatleri i\u00e7inde (8:30 - 6:00 UTC+8 Pzt.~Sat.) veya h\u0131zl\u0131 yan\u0131t almak i\u00e7in web sitesi canl\u0131 sohbetini kullan\u0131n.<\/b><\/strong><\/h4>\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n\r\n
Bile\u015fik Glukoamilaz<\/span><\/a><\/td>\r\n9032-08-0<\/td>\r\n<\/tr>\r\n
Pullulanase<\/span><\/a><\/td>\r\n9075-68-7<\/td>\r\n<\/tr>\r\n
Ksilanaz<\/span><\/a><\/td>\r\n37278-89-0<\/td>\r\n<\/tr>\r\n
Sel\u00fclaz<\/span><\/a><\/td>\r\n9012-54-8<\/td>\r\n<\/tr>\r\n
Naringinaz<\/span><\/a><\/td>\r\n9068-31-9<\/td>\r\n<\/tr>\r\n
\u03b2-Amilaz<\/span><\/a><\/td>\r\n9000-91-3<\/td>\r\n<\/tr>\r\n
Glikoz oksidaz<\/span><\/a><\/td>\r\n9001-37-0<\/td>\r\n<\/tr>\r\n
Alfa-Amilaz<\/td>\r\n9000-90-2<\/td>\r\n<\/tr>\r\n
Pektinaz<\/span><\/a><\/td>\r\n9032-75-1<\/td>\r\n<\/tr>\r\n
Peroksidaz<\/td>\r\n9003-99-0<\/td>\r\n<\/tr>\r\n
Lipaz<\/span><\/a><\/td>\r\n9001-62-1<\/td>\r\n<\/tr>\r\n
Katalaz<\/span><\/a><\/td>\r\n9001-05-2<\/td>\r\n<\/tr>\r\n
TANNASE<\/span><\/a><\/td>\r\n9025-71-2<\/td>\r\n<\/tr>\r\n
Elastaz<\/span><\/a><\/td>\r\n39445-21-1<\/td>\r\n<\/tr>\r\n
Urease<\/span><\/a><\/td>\r\n9002-13-5<\/td>\r\n<\/tr>\r\n
DEXTRANASE<\/span><\/a><\/td>\r\n9025-70-1<\/td>\r\n<\/tr>\r\n
L-Laktik dehidrojenaz<\/span><\/a><\/td>\r\n9001-60-9<\/td>\r\n<\/tr>\r\n
Dehidrojenaz malat<\/span><\/a><\/td>\r\n9001-64-3<\/td>\r\n<\/tr>\r\n
Kolesterol oksidaz<\/span><\/a><\/td>\r\n9028-76-6<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>","protected":false},"excerpt":{"rendered":"

Manyetik biyopolimer mikrok\u00fcreler, manyetik olarak duyarl\u0131 ve biyolojik olarak aktif mikrok\u00fcreler olu\u015fturmak i\u00e7in biyolojik malzemeleri ve inorganik manyetik malzemeleri birle\u015ftiren yeni bir kompozit malzemedir. \u00d6zellikleri inorganik manyetik malzemelere, biyolojik malzemelere ve bunlar\u0131n etkile\u015fim y\u00f6ntemine ba\u011fl\u0131d\u0131r. \u015eu anda en yayg\u0131n olarak kullan\u0131lan ve \u00fczerinde \u00e7al\u0131\u015f\u0131lan manyetik malzeme Fe3O4 manyetik nanopartik\u00fcllerdir. B\u00fcy\u00fck \u00f6zg\u00fcl [...] nedeniyle<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[108],"tags":[],"class_list":["post-4514","post","type-post","status-publish","format-standard","hentry","category-enzyme-news"],"yoast_head":"\nOverview of the Methods of Immobilizing Enzymes on Magnetic Biopolymer Microspheres - Longchang Chemical<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/longchangchemical.com\/tr\/overview-of-the-methods\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Overview of the Methods of Immobilizing Enzymes on Magnetic Biopolymer Microspheres - Longchang Chemical\" \/>\n<meta property=\"og:description\" content=\"Magnetic biopolymer microspheres are a novel composite material that combines biological materials and inorganic magnetic materials to form magnetically responsive and biologically active microspheres. 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