thionicotinamide cas 4621-66-3

Thionicotinamide Quick Details

Chemical Name: Thionicotinamide

CAS No.: 4621-66-3

Molecular Fomula: C6H6N2S

Chemical Structure:Thionicotinamide Structure

Molecular weight: 138.19

Appearance: Yellow crystalline powder

Assay: 99%

thionicotinamide Application scenarios

1. Pharmaceutical Intermediates (Core Applications) 💊

• Synthesis of anti-tuberculosis drugs: Participates as a key intermediate in the preparation of anti-tuberculosis drugs such as isoniazid derivatives, improving drug activity and targeting through molecular structure modification, and addressing drug resistance issues.

• Synthesis of anti-tumor drugs: Used to construct anti-tumor candidate molecules containing pyridine thioamide structures. These compounds can target and inhibit tumor cell proliferation or induce apoptosis, and are currently in the drug development and clinical trial stages.

• Synthesis of anti-inflammatory and antibacterial drugs: Used in the preparation of anti-inflammatory drug intermediates and precursors for novel antibacterial drugs targeting drug-resistant bacteria, expanding the range of anti-infective drugs.

2. Pesticide Intermediates 🚜

• Synthesis of insecticides and fungicides: Used in the preparation of pesticides containing pyridine thioamide structures, exhibiting good control effects against agricultural pests (such as aphids and planthoppers) and fungal diseases (such as powdery mildew and downy mildew).

• Synthesis of plant growth regulators: Its derivatives can regulate plant growth cycles, promote rooting, and prevent lodging, suitable for improving the quality and yield of food crops and cash crops.

3. Dye and Functional Material Synthesis 🎨

• Preparation of heterocyclic dyes: As a dye intermediate, it is used to synthesize pyridine-based acid dyes and reactive dyes, suitable for dyeing natural fibers such as wool and silk, with bright colors and excellent lightfastness.

• Synthesis of functional polymer materials: Used to prepare polymers containing thioamide groups. These materials have good heavy metal ion adsorption properties and can be applied to heavy metal removal in industrial wastewater treatment.

4. Coordination Chemistry and Catalysis Research 🧪
• Synthesis of metal complexes as ligands: The nitrogen and sulfur atoms in thioisonicotinamide can act as coordination sites, forming stable complexes with transition metals (such as copper, nickel, and palladium), used in catalytic organic synthesis reactions (such as coupling reactions and oxidation reactions).
• Used for metal ion detection: Its metal complexes have characteristic color or fluorescence properties, and can be developed as chemical probes for detecting heavy metal ions in water bodies, suitable for environmental monitoring.

Description

ThionicotinamideTypical Properties

Item Specifications
Appearance Yellow crystalline powder
Assay(HPLC) ≥98.0%
Melting point 185-190℃
Mositure ≤0.5%

ThionicotinamideUsage

Used as pharmaceutical intermediates.

  1. Chemical Synthesis: Dibutylamine, with CAS number 111-92-2, is widely used in chemical synthesis. It serves as a versatile intermediate in the production of various organic compounds, including pharmaceuticals, pesticides, and rubber chemicals.
  2. Rubber Industry: This compound finds applications in the rubber industry. Dibutylamine is used in the production of accelerators and antioxidants for rubber, contributing to the enhancement of rubber properties and performance.
  3. Pharmaceuticals: Dibutylamine is utilized in the pharmaceutical industry as an intermediate in the synthesis of certain drugs and pharmaceutical products. It serves as a building block for the production of specific active ingredients.
  4. Pesticides: In the field of agrochemicals, dibutylamine is employed in the synthesis of pesticides. It plays a role in the development of formulations that help control and eliminate pests in agriculture.

Thionicotinamide Packaging and Shipping

Packing: 1kg/Bag

Delivery: Non-dangerous cargo

Thionicotinamide Storage

Store in dry, ventilated areas to avoid direct sunlight.

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